5'-O-TERT-BUTYLDIMETHYLSILYL-THYMIDINE manufacturers
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| 5'-O-TERT-BUTYLDIMETHYLSILYL-THYMIDINE Basic information |
Product Name: | 5'-O-TERT-BUTYLDIMETHYLSILYL-THYMIDINE | Synonyms: | 5'-O-(T-BUTYLDIMETHYLSILYL)THYMIDINE;5'-O-TERT-BUTYLDIMETHYLSILYL-THYMIDINE;5'-O-tert-Butyldimethylsilylthymidine 97%;5-Methyl-5'-O-(tert-butyldimethylsilyl)-2'-deoxyuridine;5'-O-(tert-ButyldiMethylsilyl)thyMidine, 98+%;5'-O-TBDMS-thymidine;5'-O-(tert-ButyldiMethylsilyl)thyMidine, 97+%;1-((2R,4S,5R)-5-(((tert-butyldimethylsilyl)oxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione | CAS: | 40733-28-6 | MF: | C16H28N2O5Si | MW: | 356.49 | EINECS: | | Product Categories: | | Mol File: | 40733-28-6.mol | |
| 5'-O-TERT-BUTYLDIMETHYLSILYL-THYMIDINE Chemical Properties |
Melting point | 198 | density | 1.148±0.06 g/cm3(Predicted) | storage temp. | 4°C, protect from light | solubility | DMSO : 100 mg/mL (280.51 mM; Need ultrasonic) | pka | 9.55±0.10(Predicted) | form | powder | color | White |
Hazard Codes | Xi | Hazard Note | Irritant | HS Code | 2934100090 |
| 5'-O-TERT-BUTYLDIMETHYLSILYL-THYMIDINE Usage And Synthesis |
Description | 5'-O-(tert-Butyldimethylsilyl)thymidine is a synthetic nucleoside that is used as an antiviral agent in the treatment of herpes zoster and other viral infections. 5'-O-tert-Butyldimethylsilyl-D3-thymidine is a novel monophosphate, which can be activated to a diphosphate by either kinases or phosphoramidites. It has been shown to be effective against herpes virus and other DNA viruses that infect cells from various species. | Uses | 5'-O-(tert-Butyldimethylsilyl)thymidine is used as pharmaceutical intermediate. |
| 5'-O-TERT-BUTYLDIMETHYLSILYL-THYMIDINE Preparation Products And Raw materials |
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