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Products Intro: |
Product Name:Mal-PEG5-CH2CH2Mal CAS:113387-03-4 Purity:95% Package:1 g, 5 g Remarks:PEGylation Reagents
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Mal-PEG5-CH2CH2Mal manufacturers
- Mal-PEG5-Mal
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- $0.00 / 1g
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2024-03-27
- CAS:113387-03-4
- Min. Order: 1g
- Purity: >98.00%
- Supply Ability: 1g
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| Mal-PEG5-CH2CH2Mal Basic information |
Product Name: | Mal-PEG5-CH2CH2Mal | Synonyms: | Mal-PEG5-CH2CH2Mal;1H-Pyrrole-2,5-dione, 1,1'-(3,6,9,12,15-pentaoxaheptadecane-1,17-diyl)bis- | CAS: | 113387-03-4 | MF: | C20H28N2O9 | MW: | 440.44 | EINECS: | | Product Categories: | | Mol File: | 113387-03-4.mol | |
| Mal-PEG5-CH2CH2Mal Chemical Properties |
| Mal-PEG5-CH2CH2Mal Usage And Synthesis |
Biological Activity | Mal-PEG5-mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| Mal-PEG5-CH2CH2Mal Preparation Products And Raw materials |
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