Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
|
Tel: |
400-9205774 |
Email: |
sales@glpbio.cn |
Products Intro: |
Product Name:(±)10(11)-EDP Ethanolamide CAS:2123484-71-7 Purity:>98% Package:1mg;10mg;50mg;100mg;
|
Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
|
Tel: |
021-65675885 18964387627 |
Email: |
customer_service@efebio.com |
Products Intro: |
Product Name:(±)10(11)-EDP Ethanolamide CAS:2123484-71-7 Purity:98% Package:25μg;50μg;100μg
|
Company Name: |
TargetMol Chemicals Inc.
|
Tel: |
15002134094 |
Email: |
marketing@targetmol.cn |
Products Intro: |
Product Name:(±)10(11)-EDP Ethanolamide CAS:2123484-71-7 Purity:详情请点击官网 Package:1 mg
|
Company Name: |
Cayman Chemical Company
|
Tel: |
(800) 364-9897 |
Email: |
cayman@caymanchem.com |
Products Intro: |
Product Name:(±)10(11)-EDP Ethanolamide CAS:2123484-71-7
|
|
| 10,11-EDP epoxide Basic information |
Product Name: | 10,11-EDP epoxide | Synonyms: | 10,11-EDP epoxide;(±)10(11)-EDP Ethanolamide;4,7-Nonadienamide, N-(2-hydroxyethyl)-9-[3-(2Z,5Z,8Z)-2,5,8-undecatrien-1-yl-2-oxiranyl]-, (4Z,7Z)- | CAS: | 2123484-71-7 | MF: | C24H37NO3 | MW: | 387.56 | EINECS: | | Product Categories: | | Mol File: | 2123484-71-7.mol | ![10,11-EDP epoxide Structure](CAS/20181012/GIF/2123484-71-7.gif) |
| 10,11-EDP epoxide Chemical Properties |
Boiling point | 568.7±50.0 °C(Predicted) | density | 0.998±0.06 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml | pka | 14.47±0.10(Predicted) |
| 10,11-EDP epoxide Usage And Synthesis |
Description | (±)10(11)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 0.43 and 22.5 nM for CB1 and CB2 receptors, respectively). It is produced though direct epoxygenation of docosahexaenoyl ethanolamide (DHEA; ) by cytochrome P450 (CYP) epoxygenases. 10,11-EDP epoxide (12.5 and 25 μM) reduces the viability of 143B metastatic osteosarcoma cells. It induces apoptosis and inhibits cell migration in a wound-healing assay in 143B, MG63, and HOS osteosarcoma cells. (±)10(11)-EDP ethanolamide also reduces tube formation by human umbilical vein endothelial cells (HUVECs) in a Matrigel™ assay. |
| 10,11-EDP epoxide Preparation Products And Raw materials |
|