- d-phe-ol
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- $0.00/ kg
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2024-08-27
- CAS:5267-64-1
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1T+
- D(+)-Phenylalaninol
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- $0.00 / 25Kg/Drum
-
2024-08-27
- CAS:5267-64-1
- Min. Order: 1KG
- Purity: 98%min
- Supply Ability: 1000kg
- D(+)-Phenylalaninol
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- $5.00 / 1KG
-
2024-08-23
- CAS:5267-64-1
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10000kg
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| | D(+)-Phenylalaninol Chemical Properties |
| Melting point | 93-95 °C(lit.) | | Boiling point | 122 °C / 4mmHg | | alpha | 23 º (c=1.2, 1 N HCl 22 ºC) | | density | 1.0406 (rough estimate) | | refractive index | 23.5 ° (C=1.2, 1mol/L HCl) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | Soluble in Dichloromethane, Ethyl Acetate, Methanol. | | form | Crystalline Powder and Chunks | | pka | 12.85±0.10(Predicted) | | color | White to yellow | | optical activity | [α]/D +22.8°, c = 1.2 in 1 M HCl | | Sensitive | Air Sensitive | | BRN | 4665408 | | InChI | InChI=1/C9H13NO/c10-9(7-11)6-8-4-2-1-3-5-8/h1-5,9,11H,6-7,10H2/t9-/s3 | | InChIKey | STVVMTBJNDTZBF-DJEYLCQNNA-N | | SMILES | C(C1C=CC=CC=1)[C@@H](N)CO |&1:7,r| | | CAS DataBase Reference | 5267-64-1(CAS DataBase Reference) |
| Hazard Codes | C,Xi | | Risk Statements | 34 | | Safety Statements | 26-36/37/39-45-27 | | RIDADR | UN 3259 8/PG 3 | | WGK Germany | 3 | | F | 10-23 | | HazardClass | IRRITANT | | HazardClass | 8 | | PackingGroup | III | | HS Code | 29221990 |
| | D(+)-Phenylalaninol Usage And Synthesis |
| Detected method | Phenomena, including gelation and fluorescence, are used as easily detected sensors of chiral recognition. Qin et al. have developed a new type of isomerized diphenylalanine-based supramolecular gel (LFDF), which showed the visible enantiomeric discrimination of phenylalaninol enantiomers via fluorescence and gelation measurements. The addition of L- or D-phenylalaninol to the peptide gel led to complete collapse within one minute after adding the L-form, which was not observed in D-phenylalaninol. Meanwhile, by doping with the fluorescent dye thioflavin T (ThT), the prepared ThT-LFDF gel system can sensitively detect the L/D-phenylalanine enantiomer through fluorescence quenching, which has the advantages of visualization, easy manipulation, and high detection sensitivity.
| | Description | D-phenylalanine is the D-enantiomer of phenylalanine. It is a conjugate base of a D-phenylalaninium and an enantiomer of a L-phenylalanine. D-Phenylalanine is a metabolite found in or produced by Escherichia coli (strain K12, MG1655). It may be light-sensitive. This compound reacts with strong oxidizing agents, acids and bases. It acts as a weak acid in solution. | | Chemical Properties | white to light yellow crystal powde | | Uses | D-Phenylalaninol is used as a chiral auxiliary for asymmetric Michael reactions. It is an enantiomer of L-Phenylalaninol, an inhibitor of intestinal Phenylalanine absorption. It acts as an inhibiting agent to the enzymes which are responsible for the breakdown of endorphins. | | Purification Methods | It can be recrystallised from Et2O, *C6H6/pet ether (b 40-60o) or toluene and distilled in a vacuum. It has been purified by dissolving in Et2O, drying over K2CO3, filtering, evaporating to a small volume, cooling in ice and collecting the plates. Store them in the presence of KOH (i.e. CO2—free atm). [Karrer & Ehrhardt Helv Chim Acta 34 3203 1951, Oeda Bull Chem Soc Jpn 13 465 1938.] The picrate has m 141-141.5o (from EtOH/pet ether). The hydrogen oxalate has m 177o, 161-162o [Hunt & McHale J Chem Soc 2073 1957]. The racemate has m 87-88o from *C6H6/pet ether (75-77o from Et2O), and the hydrochloride has m 139-141o [Fodor et al. J Chem Soc 1858 1951]. [Beilstein 13 IV 1920.] |
| | D(+)-Phenylalaninol Preparation Products And Raw materials |
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