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| 1,2,3,4-Tetrahydro-1-naphthol Basic information |
Product Name: | 1,2,3,4-Tetrahydro-1-naphthol | Synonyms: | 1,2,3,4-tetrahydro-1-naphthaleno;1,2,3,4-Tetrahydro-1-naphthalenol;1,2,3,4-tetrahydro-1-naphtho;1,2,3,4-tetrahydro-1-napthol;1,2,3,4-Tetrahydro-alpha-naphthol;(S)-Tetralin-1-ol;(S)-Tetralin-1β-ol;1-Tetralinol | CAS: | 529-33-9 | MF: | C10H12O | MW: | 148.2 | EINECS: | 208-459-0 | Product Categories: | Building Blocks;C9 to C20+;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;Phenols | Mol File: | 529-33-9.mol | ![1,2,3,4-Tetrahydro-1-naphthol Structure](CAS/GIF/529-33-9.gif) |
| 1,2,3,4-Tetrahydro-1-naphthol Chemical Properties |
| 1,2,3,4-Tetrahydro-1-naphthol Usage And Synthesis |
Chemical Properties | clear colourless to slightly brown viscous liquid | Uses | 1,2,3,4-Tetrahydro-1-naphthol was used as chiral probe to examine the role of three aromatic residues in enzyme-substrate interactions at the sulfuryl acceptor binding site of aryl sulfotransferase IV enzyme. | Synthesis Reference(s) | The Journal of Organic Chemistry, 61, p. 1493, 1996 DOI: 10.1021/jo951219c | General Description | (R)-(-)-enantiomer of 1,2,3,4-Tetrahydro-1-naphthol is a substrate for aryl sulfotransferase (AST) IV enzyme and (S)-(+)-1,2,3,4-tetrahydro-1-naphthol is a competitive inhibitor of AST IV-catalyzed sulfation of 1-naphthalenemethanol. It is the major urinary metabolite of tetralin. |
| 1,2,3,4-Tetrahydro-1-naphthol Preparation Products And Raw materials |
Raw materials | 1,2,3,4-Tetrahydronaphthalene-->[1,1'-Binaphthalene]-1,1'(2H,2'H)-diol, 3,3',4,4'-tetrahydro--->1,2,3,4-tetrahydro-1-naphthyl hydroperoxide-->1,2,3,4-TETRAHYDRO-2-NAPHTHOL-->1,2-DIHYDRONAPHTHALENE | Preparation Products | Brodifacoum-->Flocoumafen-->Coumatetralyl-->5,6,7,8-Tetrahydronaphthalene-1-carboxylic acid-->8-BROMO-3,4-DIHYDRO-2H-NAPHTHALEN-1-ONE-->(R)-(-)-1,2,3,4-TETRAHYDRO-1-NAPHTHOL-->5,6,7,8-TETRAHYDRO-1-NAPHTHOL-->2,3,4,5-Tetrahydro-1H-benzo[b]azepine-->1,2,3,4-Tetrahydro-1-naphthylamine-->2,3-Dihydro-1,4-naphthoquinone-->(S)-(+)-1,2,3,4-Tetrahydro-1-naphthol |
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