| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
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3bsc@sina.com |
| Products Intro: |
Product Name:Gavestinel;4,6-Dichloro-3-[(1E)-3-oxo-3-(phenylaMino)-1-propenyl]-1H-indole-2-carboxylicacidsodiuMsalt
CAS:153436-22-7
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
EMMX Biotechnology LLC
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| Tel: |
888-539-0666 |
| Email: |
info@emmx.com |
| Products Intro: |
Product Name:Gavestinel
CAS:153436-22-7
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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| Company Name: |
United States Biological
|
| Tel: |
800.520.3011 or 781.639.5092 |
| Email: |
chemicals@usbio.net |
| Products Intro: |
Product Name:Gavestinel
CAS:153436-22-7
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| | 4,6-DICHLORO-3-[(1E)-3-OXO-3-(PHENYLAMINO)-1-PROPENYL]-1H-INDOLE-2-CARBOXYLIC ACID SODIUM SALT Basic information |
| | 4,6-DICHLORO-3-[(1E)-3-OXO-3-(PHENYLAMINO)-1-PROPENYL]-1H-INDOLE-2-CARBOXYLIC ACID SODIUM SALT Chemical Properties |
| Melting point | >270°C (dec.) | | Boiling point | 701.1±60.0 °C(Predicted) | | density | 1.561±0.06 g/cm3(Predicted) | | storage temp. | Desiccate at RT | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 3.77±0.30(Predicted) | | form | Solid | | color | Pale Yellow | | Stability: | Hygroscopic |
| | 4,6-DICHLORO-3-[(1E)-3-OXO-3-(PHENYLAMINO)-1-PROPENYL]-1H-INDOLE-2-CARBOXYLIC ACID SODIUM SALT Usage And Synthesis |
| Uses | Treatment of stroke (N-methylD-aspartate NMDA receptor antagonist). | | Definition | ChEBI: 3-(3-anilino-3-oxoprop-1-enyl)-4,6-dichloro-1H-indole-2-carboxylic acid is an indolyl carboxylic acid. | | Biological Activity | Highly potent and selective non-competitive antagonist acting at the strychnine-insensitive glycine binding site of the NMDA receptor-channel complex (K d = 0.8 nM). Displays > 1000-fold selectivity over NMDA, AMPA and kainate binding sites. Orally bioavailable and active in vivo . | | Safety Profile | A poison by
intravenous route. When heated to
decomposition it emits toxic vapors of NOx
and Cl-. |
| | 4,6-DICHLORO-3-[(1E)-3-OXO-3-(PHENYLAMINO)-1-PROPENYL]-1H-INDOLE-2-CARBOXYLIC ACID SODIUM SALT Preparation Products And Raw materials |
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