Company Name: |
Aikon International Limited
|
Tel: |
025-66113011 13155353615 |
Email: |
qzhang@aikonchem.com |
Products Intro: |
Product Name:proquazone CAS:22760-18-5 Purity:95+% Package:1g;5g;10g
|
Company Name: |
Shanghai Kaiwei Chemical Technology Co., Ltd.
|
Tel: |
021-58461859 15821823057 |
Email: |
service@aiviche.com |
Products Intro: |
Product Name:7-Methyl-1-(1-methylethyl)-4-phenyl-2(1H)-quinazolinone CAS:22760-18-5 Purity:95% Package:1g;1kg
|
|
| proquazone Basic information |
Product Name: | proquazone | Synonyms: | 43-715;Biarison;Biarsan;SaH-43-715;Sandoz-43-715;7-Methyl-1-(1-methylethyl)-4-phenyl-2(1H)-quinazolinone;proquazone;2(1H)-Quinazolinone, 7-methyl-1-(1-methylethyl)-4-phenyl- | CAS: | 22760-18-5 | MF: | C18H18N2O | MW: | 278.35 | EINECS: | 245-203-7 | Product Categories: | | Mol File: | 22760-18-5.mol | |
| proquazone Chemical Properties |
Melting point | 137-138° | Boiling point | 436.12°C (rough estimate) | density | 1.1707 (rough estimate) | refractive index | 1.5700 (estimate) | pka | 0.74±0.20(Predicted) |
| proquazone Usage And Synthesis |
Uses | Anti-inflammatory. | Uses | Proquazone is a non-steroidal anti-inflammatory drug. | Definition | ChEBI: Proquazone is a member of pyrimidines. | Brand name | Arthrex (Novartis), Biarison (Swiss-Pharma,
Egypt; Biochemie, Austria; ICN Alkaloida,
Hungary; Sandoz, Finland, Turkey). | Clinical Use | Proquazone has been used successfully to
treat rheumatoid polyarthritis. At 900 mg/d it
is comparable in effect to 150 mg/d of indomethacin. Gastrointestinal disturbances are
the principal adverse effects observed with its
use. | Synthesis | Synthesis: proquazone is prepared by the
alkylation of 2-amino-4-methylbenzophenone
with 2-iodopropane in the presence of
sodium carbonate to give 4-methyl-2-[(1-
methylethyl)amino]benzophenone, which is
condensed with urethane in the presence of
zinc chloride at 190 ?C.
|
| proquazone Preparation Products And Raw materials |
|