|
|
| | 1-methyl-4-nitrosopiperazine Basic information |
| Product Name: | 1-methyl-4-nitrosopiperazine | | Synonyms: | n-methyl-npz;4-Methyl-1-nitrosopiperazine;1-methyl-4-nitrosopiperazine;N-nitroso-N'-methylpiperazine;NITROSO-N-METHYLPIPERAZINE;1-NITROSO-4-METHYLPIPERAZINE;NITROSOMETHYLPIPERAZINE;N-METHYLNITROSOPIPERAZINE | | CAS: | 16339-07-4 | | MF: | C5H11N3O | | MW: | 129.16 | | EINECS: | 2404093 | | Product Categories: | | | Mol File: | 16339-07-4.mol |  |
| | 1-methyl-4-nitrosopiperazine Chemical Properties |
| Boiling point | 239.23°C (rough estimate) | | density | 1.1508 (rough estimate) | | refractive index | 1.5070 (estimate) | | solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) | | form | Oil | | pka | 6.50±0.42(Predicted) | | color | Clear Light Yellow | | Stability: | Light Sensitive |
| Toxicity | LD50 orl-rat: 100 mg/kg ZEKBAI 69,103,67 |
| | 1-methyl-4-nitrosopiperazine Usage And Synthesis |
| Uses | N-Methyl-N’-nitrosopiperazine was used as a reagent in the organic synthesis of several compounds including that of (4-methoxyphenoxy)acetic and (3,4,5-trimethoxyphenoxy)acetic acid amides and hydrazides which display antimicrobial and anthelmintic properties and may act as potential neurotropic and cardiovascular agents. N-Methyl-N’-nitrosopiperazine also diplayed strong nasal carcinogenity and genotoxicity toward nasal cells. | | Safety Profile | Poison by ingestion.
Questionable carcinogen with experimental
tumorigenic data. Mutation data reported.
Many N-nitroso compounds are
carcinogens. When heated to decomposition
it emits toxic fumes of NOx. See also NNITROSO
COMPOUNDS. |
| | 1-methyl-4-nitrosopiperazine Preparation Products And Raw materials |
|