Welcome to chemicalbook!
+1 (818) 612-2111
Inquriy
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

RFQ
skype
MY Account
Top
Postion:Product Catalog >Organic Chemistry>Alcohols,Phenols,Phenol alcohols>1-(5-Fluoro-2-hydroxyphenyl)-1-ethanone
1-(5-Fluoro-2-hydroxyphenyl)-1-ethanone
  • 1-(5-Fluoro-2-hydroxyphenyl)-1-ethanone

1-(5-Fluoro-2-hydroxyphenyl)-1-ethanone

Price Get Latest Price
Package 1KG
Min. Order: 0.1KG
Supply Ability: 1000KGS
Update Time: 2023-06-14

Product Details

Product Name: 1-(5-Fluoro-2-hydroxyphenyl)-1-ethanone CAS No.: 500-49-2
Min. Order: 0.1KG Purity: 99%
Supply Ability: 1000KGS Release date: 2023/06/14

Welcome to inquire.       Email: sales@anbuchem.com    Whatsapp: +86 18638608485


5-Propyl-1,3-benzenediol Basic information

Product Name: 5-Propyl-1,3-benzenediol

Synonyms: 5-Propyl-1,3-benzenediol;Divarinol;1,3-Benzenediol, 5-propyl-;3,5-Dihydroxypropylbenzene;1,3-Benzenediol, 5-propyl- CAS NO.500-49-2;3,5-Dihydroxy-1-propylbenzene;Divarin

CAS: 500-49-2

MF: C9H12O2

MW: 152.19

EINECS:

Product Categories:

Mol File: 500-49-2.mol

5-Propyl-1,3-benzenediol Structure

5-Propyl-1,3-benzenediol Chemical Properties

Melting point 82.8°C

Boiling point 234.66°C (rough estimate)

density 1.0505 (rough estimate)

refractive index 1.4024 (estimate)

solubility DMF: 2 mg/ml; DMSO: 2 mg/ml; Ethanol: 5 mg/ml; PBS (pH 7.2): 1 mg/ml

form A crystalline solid

pka 9.56±0.10(Predicted)

InChI InChI=1S/C9H12O2/c1-2-3-7-4-8(10)6-9(11)5-7/h4-6,10-11H,2-3H2,1H3

InChIKey FRNQLQRBNSSJBK-UHFFFAOYSA-N

SMILES C1(O)=CC(CCC)=CC(O)=C1

Safety Information

HS Code 2907290090

MSDS Information

5-Propyl-1,3-benzenediol Usage And Synthesis

Description A White to Brown crystalline solid.

Uses 5-Propylbenzene-1,3-diol is an intermediate used to prepare Cannabigerovarin (C175140) which stimulates thermosensitive transient receptor potential (TRP) channels of vanilloid type-4 (TRPV4)-mediated [Ca2+]i with moderate-high efficacy (30-60% of the effect of ionomycin) and potency (EC50 0.9-6.4 μM),

Definition ChEBI: Divarinol is a 5-alkylresorcinol in which the alkyl group is specified as propyl. It has a role as a semiochemical, a fungal metabolite, a lichen metabolite and an animal metabolite.

Synthesis In a 100 mL round bottom flask, open to the atmosphere was added the crude product Benzene, 1,3-dimethoxy-5-propyl (0.736 g, 4.08 mmol, 1.0 equiv.) and a 1:1 mixture of glacial acetic acid (20 mL, 349.7 mmol, 17.4 M) and hydrobromic acid (48% in H2O, 20 mL, 368.3 mmol, 18.4 M). The reaction mixture was refluxed at 125 °C for 3 hours while stirring, or until the starting material was consumed via TLC analysis. At this point, the reaction was allowed to cool to room temperature and quenched by the addition of DI H2O. The biphasic solution was added to a separatory funnel, wherein the organic portion was extracted Et2O (ca. 3x 20 mL). The organic layers were then combined, neutralized with a concentrated sodium bicarbonate solution (ca. 30 mL), washed with a saturated brine solution (ca. 50 mL), dried over MgSO4, filtered, and concentrated in vacuo to afford the final product without 5-Propyl-1,3-benzenediol (0.609 g, 99% yield) as a pale yellow oil.

500-49-2.png

Solubility in organics 5-Propyl-1,3-benzenediol is soluble in N,N-dimethylformamide, soluble in methanol, slightly soluble in glacial acetic acid, very slightly soluble in chloroform, almost insoluble in water.

5-Propyl-1,3-benzenediol Preparation Products And Raw materials

Raw materials 1-(3,5-dimethoxyphenyl)propan-1-one-->Benzeneethanol, 3,5-dimethoxy-α-methyl--->1,3-Benzenediol, 5-(2-propen-1-yl)--->1-(3,5-dimethoxyphenyl)propan-1-ol-->1,3-dimethoxy-5-propylbenzene-->Ethyl divarinolcarboxylate-->2-Hydroxy-4-oxo-6-propyl-2-cyclohexene-1-carboxylic Acid Methyl Ester-->ETHYL 3,5-DIMETHOXYBENZOATE-->3,5-Dimethoxybenzyl alcohol-->1-Bromo-3,5-dimethoxybenzene-->3,5-Dimethoxybenzoic acid-->3,5-DIMETHOXYBENZOYL CHLORIDE-->3,5-Dimethoxybenzaldehyde

Preparation Products (+)-2-Methyl-2-(4-methyl-3-pentenyl)-7-propyl-2H-1-benzopyran-5-ol


Company Profile Introduction

Anbu Chem is a leading provider of fine chemical manufacturing services. Our highly qualified and experienced expert team has been providing quality products and services to pharmaceutical companies, research laboratories, and other industries worldwide for over ten years. We specialize in manufacturing of a wide range of fine chemicals and pharmaceutical intermediates, including active pharmaceutical ingredients (API), intermediates, and excipients. Our commitment to quality, along with our expertise in chemical engineering, has allowed us to develop and manufacture products using the latest technologies, processes, and techniques. At Anbu Chem, our customers can rely on us for the quality assurance and safety of their products. We take our commitment to quality seriously and strive to ensure that each batch of chemicals is manufactured to the highest standards.

You may like

Recommended supplier

Product name Price   Suppliers Update time
$5.90/1kg
VIP1Y
Shandong Deshang Chemical Co., Ltd.
2024-06-26
$1.00/1kg
VIP1Y
Xiamen Work-For-World Medicine Co.,Ltd.
2024-03-27
$0.00/1kg
VIP1Y
Chongqing Zhihe Biopharmaceutical Co., Ltd.
2024-01-02
$50.00/1KG
VIP1Y
Henan Fengda Chemical Co., Ltd
2023-12-22
$0.00/25KG
VIP5Y
Hebei Mojin Biotechnology Co., Ltd
2023-09-07
$0.00/25KG
VIP2Y
Hebei Guanlang Biotechnology Co., Ltd.
2022-10-28
$10.00/1KG
VIP6Y
Hebei Guanlang Biotechnology Co., Ltd.
2022-10-27
$0.00/1KG
VIP2Y
Henan Aochuang Chemical Co.,Ltd.
2022-09-19
$0.00/25kg
PNP Biotech Co. Ltd
2022-09-14
$0.00/1kg
VIP3Y
Jiangsu Nata Opto-electronic Material Co.,Ltd.
2022-04-28
  • Since: 2019-12-09
  • Address: No 10 Yuying Road, Guancheng District, Zhengzhou 450000, China
INQUIRY

+86-15988602810
sales@anbuchem.com