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Apixaban NEW
Price | Get Latest Price | ||
Package | 1Kg/Bag | 25Kg/Bag | 100Kg/Bag |
Min. Order: | 1Kg/Bag |
Supply Ability: | 20 tons |
Update Time: | 2024-08-22 |
Product Details
Product Name: Apixaban | CAS No.: 503612-47-3 |
EC-No.: 639-684-6 | Min. Order: 1Kg/Bag |
Purity: 99% up, High Density | Supply Ability: 20 tons |
Release date: 2024/08/22 |
Product Information
Product name | Apixaban |
CAS | 503612-47-3 |
MF | C25H25N5O4 |
MW | 459.50 |
MOQ | 100g |
Test Method | HPLC |
Purity | 99% |
Appearance | White Crystalline Powder |
Shelf life | 2 years |
Storage | Cool and dry place |
Apixaban is a highly selective, reversible, and direct inhibitor of Human Factor X and Rabbit Factor X with Ki of 0.08 nM and 0.17 nM, respectively. Apixaban exhibits a high degree of potency, selectivity, and efficacy on Factor X with Ki of 0.08 nM and 0.17 nM for Human Factor X and Rabbit Factor X, respectively. In vitro, Apixaban prolongs the clotting times of normal human plasma with theconcentrations (EC2x) of 3.6 μM, 0.37 μM, 7.4 μM, and 0.4 μM, which are required respectively to double the prothrombin time (PT),modified prothrombin time (mPT), activated partial thromboplastin time (APTT) and HepTest. Besides, Apixaban shows the highestpotency in human and rabbit plasma, but less potency in rat and dog plasma in both the PT and APTT assays.
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- Since: 1996-07-16
- Address: Fujian China ,16F, Huicheng Comm. Complex, 839 Xiahe RD.