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Postion:Product Catalog >Biochemical Engineering>Inhibitors>Metabolism>Factor Xa inhibitor>Apixaban
Apixaban
  • Apixaban
  • Apixaban
  • Apixaban
  • Apixaban
  • Apixaban

Apixaban NEW

Price $30 $25 $20
Package 1box 5box 10box
Min. Order: 1box
Supply Ability: 1000box
Update Time: 2024-07-26

Product Details

Product Name: Apixaban CAS No.: 503612-47-3
EC-No.: 639-684-6 Min. Order: 1box
Purity: 99.9+ Supply Ability: 1000box
Release date: 2024/07/26
ItemsSpecifications
Chemical FormulaC25H25N5O4
Molecular Weight459.5 g/mol
CAS Number503612-47-3
IUPAC Name1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
AppearanceWhite to off-white powder
Melting Point235-238°C
SolubilitySoluble in organic solvents, slightly soluble in water
StabilityStable under recommended storage conditions
StorageStore in a tightly closed container, in a dry place, at room temperature
UsageAnticoagulant
Pharmacological ClassFactor Xa inhibitor
Mechanism of ActionSelectively inhibits factor Xa, thereby inhibiting thrombin generation and preventing blood clot formation
Half-LifeApproximately 12 hours in healthy individuals
Route of AdministrationOral
BioavailabilityApproximately 50%
Protein BindingApproximately 87%
MetabolismPrimarily hepatic metabolism via CYP3A4 and CYP3A5
ExcretionRenal (27%) and fecal (66%)
Dosage FormsTablets (2.5 mg, 5 mg)
Onset of ActionWithin 3 hours after oral administration
Duration of ActionApproximately 12-24 hours


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