4'-N-benzoylstaurosporine
| Price | $2 |
| Package | 1kg |
| Min. Order: | 1kg |
| Supply Ability: | 100kg |
| Update Time: | 2019-07-06 |
Product Details
| Product Name: 4'-N-benzoylstaurosporine | CAS No.: 120685-11-2 |
| Min. Order: 1kg | Purity: 99% |
| Supply Ability: 100kg | Release date: 2019/07/06 |
| Product NUmber: : WM.562 |
| 4'-N-benzoylstaurosporine Basic information |
| Product Name: | 4'-N-benzoylstaurosporine |
| Synonyms: | 4'-N-benzoylstaurosporine;Midostaurin, Benzoylstaurosporine, 4'-N-Benzoylstaurosporine, CGP 41251;Benzamide, N-((9S,10R,11R,13R)-2,3,9,10,11,12-hexahydro-10-methoxy-9-methyl-1-oxo-9,13-epoxy-1H,9H-diindolo(1,2,3-gh:3',2',1'-lm)pyrrolo(3,4-J)(1,7)benzodiazonin-11-yl)-N-methyl-;Benzamide, N-(2,3,9,10,11,12-hexahydro-9-methoxy-8-methyl-1-oxo-8,12-epoxy-1H,8H-2,7B,12A-triazadibenzo(A,G)cyclonona(cde)trinden-10-yl)-N-methyl-, (8alpha,9beta,10beta,12alpha)-;Benzoylstaurosporine;Cgp 41 251;Cgp 41251;Cgp-41251 |
| CAS: | 120685-11-2 |
| MF: | C35H30N4O4 |
| MW: | 570.646 |
| EINECS: | 999-999-2 |
| Product Categories: | antibiotic |
| Mol File: | 120685-11-2.mol |
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| 4'-N-benzoylstaurosporine Chemical Properties |
| Melting point | 235-260℃ |
| storage temp. | Store at 2-8 |
| solubility | Soluble in DMSO (15 mg/ml), MDC (10 mg/ml), methanol (5 mg/ml), 100% ethanol (2.5 mg/ml), and DMF (20 mg/ml). |
| Safety Information |
| Hazard Codes | T |
| Risk Statements | 36/37/38 |
| MSDS Information |
| 4'-N-benzoylstaurosporine Usage And Synthesis |
| Uses | Midostaurin was shown to possess antiproliferative characteristics via inhibition of protein kinase C, kinase insert domain receptor, and c-kit. |
| Definition | ChEBI: An organic heterooctacyclic compound that is the N-benzoyl derivative of staurosporine. |
| Biological Activity | Broad spectrum protein kinase inhibitor. Inhibits conventional PKC isoforms ( α , β , γ ), PDFR β , VEGFR2, Syk, PKCη, Flk-1, Flt3, Cdk1/B, PKA, c-Kit, c-Fgr, c-Src, VEGFR1 and EGFR. Displays potent antitumor activity. |
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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China- Since: 2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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sales@coreychem.com