6-azido-6-deoxy-d-galactose

Description of 6-azido-6-deoxy-d-galactose from Watson Biotechnology Co., Ltd

Applications of 6-azido-6-deoxy-d-galactose CAS 66927-03-5 use for Bioorthogonal Chemistry Molecular Probes and Diagnostics

6-Azido-6-deoxy-D-galactose is a synthetic sugar derivative where an azide group replaces the hydroxyl group at the sixth position of D-galactose. This modification imparts unique properties to the sugar, enabling various specialized applications in research and biotechnology. Here are some key applications:

 1. Bioorthogonal Chemistry:

   - Click Chemistry: The azido group in 6-Azido-6-deoxy-D-galactose is reactive in click chemistry, specifically in the copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction. This allows for the conjugation of the sugar with various molecules, such as fluorescent dyes or biomolecules, making it useful for labeling and imaging studies.

 2. Glycobiology:

   - Metabolic Labeling: 6-Azido-6-deoxy-D-galactose can be incorporated into glycans in living cells. Researchers can use this to study glycan biosynthesis, track glycoproteins, and analyze glycan function in cells by subsequently reacting the azido group with a detectable probe.

 3. Drug Delivery:

   - Targeted Delivery Systems: The azido group can be used to attach therapeutic agents to specific sugar molecules. These conjugates can then target particular cells or tissues, improving the specificity and efficacy of drug delivery.

 4. Molecular Probes and Diagnostics:

   - Imaging and Detection: The azido group can be conjugated with various probes for imaging purposes. These modified sugars can help visualize biological processes in cells or tissues using fluorescence or other detection methods.

 5. Polymer and Material Science:

   - Functionalized Polymers: 6-Azido-6-deoxy-D-galactose can be used to create azido-functionalized polymers, which can then be used in material science for creating smart materials or in surface modifications.

Overall, 6-Azido-6-deoxy-D-galactose is a versatile tool in chemical biology, offering numerous applications in research, diagnostics, and therapeutic development.

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