8-ETHYL-5,8-DIHYDRO-5-OXO-2-[1-PIPERAZINYL]PYRIDO[2,3-D]-PYRIMIDINE-6-CARBOXYLIC ACID

Piperate name

The Chinese name is piperic acid

The English name is pipemidic acid

Chinese alias pyrazole bligh acid | 8 - ethyl - 5, 8 - dihydro - 5 - oxygen - 2 - (1 - piperazine) - pyridine [2, 3 - D] - 6 - carboxylic acid and thymine

More English nicknames

Biological activity of piperate acid

Pipemidic acid is a new antibacterial agent against Bacillus aeruginosa.

Related category

Signal path > > Anti-infection > > bacteria

Research Field > > infection

Physical and chemical properties of piperate acid

Density 1.4± 0.1g /cm3

Boiling point 534.9±60.0 °C at 760 mmHg

Molecular formula C14H17N5O3

Molecular weight 303.316

Flash point 277.3±32.9 °C

Accurate mass 303.133148

PSA 100.35,000

LogP minus 0.16

Appearance properties white to off-white powder

Vapor pressure 0.0±1.5 mmHg at 25°C

Refractive index 1.617

Storage condition

Keep the storage device sealed and stored in a cool, dry place. Ensure that the workshop is well ventilated or vented

stability

Will not decompose if used and stored according to specifications. No known hazardous reactions

Computational chemistry

1. Reference value for calculating hydrophobic parameters (XlogP) : None

2. Number of hydrogen bond donors :2

3. Number of hydrogen bond receptors :8

4. Number of rotatable bonds :3

5. Number of tautomers: None

6. Topological molecular polar surface area 98.7

7. Number of heavy atoms :22

8. Surface charge :0

9. Complexity :489

10. Number of isotope atoms :0

11. Determine the number of primary constitutive centers :0

12. Number of indeterminate atomic orthotropic centers :0

13. Determine the number of chemical bond constitutive centers :0

14. Number of uncertain bond constitutive centers :0

15. Number of covalent bond units :1

more

1. Character: not determined

2. Density (g/mL,25ºC) : Not determined

3. Relative vapor density (g/mL, air =1) : not determined

4. Melting point (ºC) : Not determined

5. Boiling point (ºC) : Not determined

6. Boiling point (ºC, 0.3mm hg) : Not determined

7. Refractive index: not determined

8. Flash point (°F) : Not determined

9. Specific rotation (ºC) : Not determined

10. Spontaneous ignition point or ignition temperature (ºC) : not determined

11. Vapor pressure (kPa,20ºC) : Not determined

12. Saturated vapor pressure (kPa,60ºC) : Not determined

13. Heat of combustion (KJ/mol) : not determined

14. Critical temperature (ºC) : Not determined

15. Critical pressure (KPa) : Not determined

16. Logarithmic value of oil-water (octanol/water) partition coefficient: not determined

17. Upper explosion limit (%,V/V) : Not determined

18. Lower explosive Limit (%,V/V) : Not determined

19. Solubility: not determined