D-(-)-Salicin NEW

Description of D-(-)-Salicin from Wuhan Fortuna Chemical Co.,Ltd

Specifications(COA) of Factory Supply D-(-)-Salicin Powder CAS 138-52-3 Cosmetic Grade Nutrition Supplement

Introduction of D-(-)-Salicin.

D-(-)-Salicin is a naturally occurring compound that belongs to the class of glycosides. It is specifically a β-D-glucoside of salicyl alcohol. The structure of D-(-)-Salicin consists of a glucose molecule (a sugar) linked to a salicyl alcohol (a type of phenolic alcohol).

Here are some key points about D-(-)-Salicin:

Chemical Structure: The chemical formula of D-(-)-Salicin is C13H18O7. It has a glucose moiety attached to a salicyl alcohol via a β-glycosidic bond.

Natural Source: D-(-)-Salicin is found in the bark of willow trees (genus Salix) and other plants. It is one of the active components responsible for the medicinal properties of willow bark.

Historical Significance: Salicin is historically significant because it was one of the first compounds used in the development of aspirin (acetylsalicylic acid). The hydrolysis of salicin yields salicylic acid, which is a precursor to aspirin.

Physical Properties: D-(-)-Salicin is typically a white crystalline powder that is soluble in water and has a bitter taste.

Stereochemistry: The "D-(-)" notation indicates the specific stereochemistry of the glucose part of the molecule. “D” refers to the configuration of the glucose molecule, and "(-)" indicates that the compound is levorotatory, meaning it rotates plane-polarized light to the left.

While you requested no applications, it’s worth noting that understanding the structure and properties of D-(-)-Salicin is essential for various fields, including organic chemistry, pharmacology, and natural product research.

Application of D-(-)-Salicin.

D-(-)-Salicin has several notable applications, primarily due to its medicinal properties and historical significance. Here are some of the key applications:

Analgesic and Anti-inflammatory: D-(-)-Salicin is known for its pain-relieving and anti-inflammatory properties. It is metabolized in the body to salicylic acid, which is a precursor to aspirin. This makes it useful in the treatment of conditions like headaches, muscle pain, and arthritis.

Antipyretic: Salicin has fever-reducing properties. It has been traditionally used to lower fever in various cultures, particularly in the form of willow bark tea.

Historical Use in Medicine: Before the synthesis of aspirin, willow bark extracts containing salicin were commonly used in traditional medicine to treat pain and inflammation. The discovery and use of salicin paved the way for the development of modern nonsteroidal anti-inflammatory drugs (NSAIDs).

Pharmaceutical Research: D-(-)-Salicin is used in pharmaceutical research as a natural product model for studying the metabolism and pharmacokinetics of salicylates. It helps in understanding how similar compounds are processed in the body.

Nutraceuticals and Herbal Supplements: Salicin is found in various herbal supplements and nutraceutical products aimed at providing natural pain relief and anti-inflammatory benefits. These products often use willow bark extract as a source of salicin.

Cosmetics: Due to its anti-inflammatory properties, salicin is sometimes included in cosmetic formulations to help soothe irritated skin and reduce redness.

Biochemical Studies: In biochemical and pharmacological studies, D-(-)-Salicin is used as a reference compound to investigate the mechanisms of action of salicylates and related compounds.

Traditional Medicine: In various traditional medicine systems, such as Chinese and Native American medicine, willow bark containing salicin has been used for centuries to treat a variety of ailments, including pain, fever, and inflammation.

Overall, D-(-)-Salicin is a compound of significant historical and contemporary interest, with applications spanning from traditional medicine to modern pharmacology and beyond.

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