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Postion:Product Catalog >Keap1-Nrf2-IN-15
Keap1-Nrf2-IN-15
  • Keap1-Nrf2-IN-15

Keap1-Nrf2-IN-15 NEW

Price $1520 $1980 $2500
Package 25mg 50mg 100mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Keap1-Nrf2-IN-15 CAS No.: 2456295-45-5
Supply Ability: 10g Release date: 2024/11/19

Product Introduction

Bioactivity

NameKeap1-Nrf2-IN-15
DescriptionKeap1-Nrf2-IN-15 (Compound 24a) is a potent inhibitor of the Keap1-Nrf2 protein-protein interaction, with IC50 values of 77 nM in a fluorescence polarization (FP) assay and 2.5 nM in a time-resolved fluorescence resonance energy transfer (TR-FRET) assay [1].
In vitroKeap1-Nrf2-IN-15 (Compound 24a) binds to Keap1 protein [1] and, at concentrations of 10 and 100 μM for 24 hours, significantly induces the expression of Nrf2 target genes (HMOX1, GSTM3, NQO1) in NCM460D cells [1].
StorageShipping with blue ice.

Company Profile Introduction

TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds. 170+ Compound Libraries, 10000+ Noval Small Molecucles,16000+ Nature Compounds TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.

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