ChemicalBook >>Cantharidin>>Dimethyl-3,6-epoxyperhydrophthalic anhydride(56-25-7)

Dimethyl-3,6-epoxyperhydrophthalic anhydride(56-25-7)

Dimethyl-3,6-epoxyperhydrophthalic anhydride(56-25-7)
Product IdentificationBack to Contents
【Product Name】

Dimethyl-3,6-epoxyperhydrophthalic anhydride
【Synonyms】

1,2-Dimethyl-3,6-Epoxyperhydrophthalic anhydride
CAN
Cantharides camphor
Cantharidin
Cantharone
Exo-1,2-cis-dimethyl-3,6-Epoxyhexahydrophthalic anhydride
【CAS】

56-25-7
【Formula】

C10H12O4
【Molecular Weight】

196.2
【EINECS】

200-263-3
【RTECS】

RN8575000
【RTECS Class】

Agricultural Chemical and Pesticide; Tumorigen; Drug; Human Data; Natural Product
【Merck】

12,1797
【Beilstein/Gmelin】

85302
【Beilstein Reference】

5-19-05-00051
Physical and Chemical PropertiesBack to Contents
【Appearance】

White crystals.
【Solubility in water】

insoluble in cold water
【Melting Point】

217
【Density】

1.41 g/cm3
【Usage】

Used for the removal of warts.
First Aid MeasuresBack to Contents
【Ingestion】

Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
【Inhalation】

If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
【Skin】

Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists.
【Eyes】

Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.
Handling and StorageBack to Contents
【Storage】

Keep in a sealed container. Place in a poison cabinet with controlled access.
【Handling】

Do not open container without reading the MSDS. This material is very expensive, costing about $500,000 for less than 100 mg. Always handle while while using protective equipment. Always use in a chemical fume hood. This material is a very, very toxic material.
Hazards IdentificationBack to Contents
【Inhalation】

Dangerous to respiratory tract.
【Skin】

Mild to severe reactions may be seen. Cantharidin is a vesicant and may cause blisters within 4 to 5 hours of application. Acantholysis may be seen. Cantharidin has been used in vivo to induce acantholysis.
【Eyes】

Inflammation of the eye, keratitis, iritis, and edema of the lids has been noted. A burning sensation of the mouth and throat after ingestion is common. Swelling and blistering of the tongue may be seen.
【Ingestion】

Extremely poisonous.
【Hazards】

When heated to decomposition it emits acrid smoke and irritating fumes.
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
【Respirators】

Dust mask.
【Exposure Effects】

Abnormally low blood pressure may develop with severe poisonings. Heart rate and respiration may be initially stimulated and then depressed. Neurologic effects include delirium, syncope, ataxia, coma, and occasionally seizures and flaccid paralysis.
【Poison Class】

1
Fire Fighting MeasuresBack to Contents
【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Wearing protective equipment, swap up small quantites with a pad moistened with a mild alkali. Collect and transfer the swabs for waste disposal. Clean surfaces with a solution of sodium hydroxide.
Stability and ReactivityBack to Contents
【Stability】

Stable at normal temperatures and pressures.
【Incompatibilities】

Strong oxidizing agents.
【Decomposition】

Very toxic fumes.
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