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Amoxapine(14028-44-5)

Amoxapine(14028-44-5)
Product IdentificationBack to Contents
【Product Name】

Amoxapine
【Synonyms】

2-Chloro-11-(1-piperazinyl)dibenz[b,f][1,4]oxazepine
8-Chloro-6-piperazin-1-ylbenzo[b][1,5]benzoxazepine
Amoxan
Asendin
Moxadil
【CAS】

14028-44-5
【Formula】

C17H16ClN3O
【Molecular Weight】

313.79000000000002
【EINECS】

237-867-1
【RTECS】

HQ4025500
【RTECS Class】

Drug; Human Data
【Merck】

12,616
【Beilstein/Gmelin】

832057
【Beilstein Reference】

6-27
Physical and Chemical PropertiesBack to Contents
【Appearance】

White solid
【Solubility in water】

Insoluble
【Melting Point】

175 - 176
【Boiling Point】

470
【Vapor Pressure】

5E-9 (25 C)
【pKa/pKb】

5.97 (pKb)
【Heat Of Vaporization】

73.2 kJ/mol
【Usage】

Tricyclic antidepressant.
First Aid MeasuresBack to Contents
【Ingestion】

If swallowed, wash out mouth with water provided person is conscious. Call a physician.
【Inhalation】

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
【Skin】

In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
【Eyes】

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
Handling and StorageBack to Contents
【Storage】

Keep tightly closed.
Hazards IdentificationBack to Contents
【Inhalation】

May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
【Skin】

May cause skin irritation.
【Eyes】

May cause eye irritation.
【Ingestion】

Harmful if swallowed.
【Hazards】

Emits toxic fumes under fire conditions.
【EC Risk Phrase】

22
【EC Safety Phrase】

36
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Wear self-contained breathing apparatus, rubber boots, and heavy rubber gloves.
【Exposure Effects】

Harmful if swallowed. Calif. Prop. 65 reproductive hazard. Target organ(s): Heart. Central nervous system.
Fire Fighting MeasuresBack to Contents
【Flash Point】

238
【Fire Fighting】

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability and ReactivityBack to Contents
【Stability】

Stable at normal temperatures and pressures.
【Incompatibilities】

Strong oxidizing agents.
【Decomposition】

Carbon monoxide, Carbon dioxide, Nitrogen oxides.
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