Name: PF-06952229
CAS#: 1801333-55-0
Chemical Formula: C23H24ClFN4O3
Exact Mass: 458.1521
Molecular Weight: 458.9184
Elemental Analysis: C, 60.20; H, 5.27; Cl, 7.72; F, 4.14; N, 12.21; O, 10.46
Description: PF-06952229 is a potent, selective and orally active TGFbR1 inhibitor. PF-06952229 specifically binds to TGFbR1 and prevents TGFbR1-mediated signal transduction. PF-06952229 is a promising antineoplastic agent for the study solid tumors, especifically metastatic breast cancer.
IUPAC/Chemical Name: 4-((2-(5-chloro-2-fluorophenyl)-5-isopropylpyridin-4-yl)amino)-N-(1,3-dihydroxypropan-2-yl)nicotinamide
InChi Key: IPBLCOKXDQHSQW-UHFFFAOYSA-N
InChi Code: InChI=1S/C23H24ClFN4O3/c1-13(2)17-10-27-21(16-7-14(24)3-4-19(16)25)8-22(17)29-20-5-6-26-9-18(20)23(32)28-15(11-30)12-31/h3-10,13,15,30-31H,11-12H2,1-2H3,(H,28,32)(H,26,27,29)
SMILES Code: O=C(NC(CO)CO)C1=CN=CC=C1NC2=CC(C3=CC(Cl)=CC=C3F)=NC=C2C(C)C
Appearance: Solid powder
关键字： 1801333-55-0;PF-06952229;
北京百奥创新科技有限公司是一家专注于生命科学的科技企业，由在国内科研试剂领域有着丰富从业经验的技术团队和管理团队组建而成，专营进口生物试剂，科学仪器，实验消耗品等。公司与诸多国外品牌签下代理，RD、Abcam、CST、Genetex、Biolegend、ebioscience、polypure、polyplus、Bethyl、Novus等，能为广大科研用户提供数万种试剂、仪器和实验消耗品。
公司将不断把上优质的产品引入国内市场，满足客户的需求，公司也将紧跟生命科学的发展，为广大科研工作者探索生命科学的奥秘奉献绵薄之力！