产品属性:
产品名称
规格
CAS号
型号
4-Octyl Itaconate
10mM*1mLinDMSO 50mg 100mg 200mg 500mg
3133-16-2
EY-Y0165145
Cas No.3133-16-2
别名 N/A
化学名 N/A
分子式 C13H22O4
分子量 242.31
溶解度 DMSO : ≥ 150 mg/mL (619.04 mM)
储存条件 Store at -20°C General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request 产品描述: 4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
4-Octyl Itaconate (OI) is a cell-permeable itaconate derivative. 4-Octyl Itaconate is protective against lipopolysaccharide-induced lethality in vivo and decreases cytokine production[1].
[1]. Mills EL, et al. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. Nature. 2018 Apr 5;556(7699):113-117.
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