产品属性:
产品名称 | 规格 | CAS号 | 型号 |
4-bromo A23187 | 1mg 5mg 10mg | 76455-48-6 | EY-Y0165146 |
Cas No.76455-48-6
别名 4-Bromocalcimycin
化学名 6-bromo-5-(methylamino)-2-[[(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]methyl]-4-benzoxazolecarboxylic acid
分子式 C29H36BrN3O6
![4-bromo A23187.png 4-bromo A23187.png](/SupplyImg/2022-11-28/6380524929667199036856020.jpg)
分子量 602.5
溶解度 1mg/mL in DMSO, 10mg/mL in DMF
储存条件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述:
4-bromo A23187 is a halogenated analog of the highly selective calcium ionophore A23187. 4-bromo A23187 is non-fluorescent.[1] As a result, it is often used in experiments where fluorescent probes are employed.[2],[3]
Reference:
[1]. Deber, C.M., Tom-Kun, J., Mack, E., et al. Bromo-A23187: A nonfluorescent calcium ionophore for use with fluorescent probes. Anal.Biochem. 146(2), 349-352 (1985).
[2]. Ducreux, S., Gregory, P., and Schwaller, B. Inverse regulation of the cytosolic Ca2+ buffer parvalbumin and mitochondrial volume in muscle cells via SIRT1/PGC-1α axis. PLoS One 7(9), (2012).
[3]. Yang, J., Singh, V., Cha, B., et al. NHERF2 protein mobility rate is determined by a unique C-terminal domain that is also necessary for its regulation of NHE3 protein in OK cells. J.Biol.Chem. 288(23), 16960-16974 (2013).
关键字: 76455-48-6;C29H36BrN3O6;4-bromo A23187;
上海一研生物科技有限公司Shanghai yiyan bio-technology Co. Ltd.主要从事免疫学、分子生物学和常规生化试剂等为一体的科研产品销售企业,公司自成立以来,秉承""全心全意服务于科研工作者""的企业理念,立足生物科技领域,运用生物技术和科研试剂,发展现代生物科技,为各类大中小医院及其它医疗机构、高等院校、科研院所、企事业单位提供优质的产品,服务生物科技领域的科学研究人员。
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