Product Name:Kaliotoxin
CAS No.:145199-73-1
Synonyms:强效阻断剂Kaliotoxin
Catalog No.:218P199
Brand:HongTide(上海鸿肽生物)
Description:Kaliotoxin是由38个氨基酸组成的环状多肽,序列中含有3对二硫键,是电压敏感 K+ 通道的强效阻断剂(KV1.3、KV1.1 和 KV1.2 通道的 IC50 值分别为 0.1、1.1 和 25 nM),Kaliotoxin还抑制 Ca2+ 激活的 K+ 通道。
Kaliotoxin is a cyclic peptide composed of 38 amino acids, containing 3 pairs of disulfide bonds in its sequence. It is a powerful blocker of voltage sensitive K+channels (IC50 values of 0.1, 1.1, and 25 nM for KV1.3, KV1.1, and KV1.2 channels, respectively). Kaliotoxin also inhibits Ca2+activated K+channels.
Purity (HPLC) ≥95.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | GVEINVKCSGSPQCLKPCKDAGMRFGKCMNRKCHCTPK(Disulfide bridge:Cys8-Cys28;Cys14-Cys33;Cys18-Cys35) |
Sequence(3-letter code) | H-Gly-Val-Glu-Ile-Asn-Val-Lys-Cys-Ser-Gly-Ser-Pro-Gln-Cys-Leu-Lys-Pro-Cys-Lys-Asp-Ala-Gly-Met-Arg-Phe-Gly-Lys-Cys-Met-Asn-Arg-Lys-Cys-His-Cys-Thr-Pro-Lys-OH(Disulfide bridge:Cys8-Cys28;Cys14-Cys33;Cys18-Cys35) |
Peptide Structure | ![Kaliotoxin 145199-73-1.png Kaliotoxin 145199-73-1.png](/SupplyImg/2023-05-03/6381870435650398468717924.jpg)
|
Molecular Formula | C171H283N55O49S8 |
Molecular Weight | 4149.96 |
订购联系方式:
上海鸿肽生物科技有限公司
手机: +86-18018095145 (同微信号)
QQ: 3259098395
邮箱:sales1@hongtide.com
关键字: 145199-73-1;强效阻断剂Kaliotoxin;Kaliotoxin ;多肽;多肽合成;
上海鸿肽生物科技有限公司(简称:鸿肽生物)是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖:定制多肽、目录多肽、氨基酸衍生物、小分子化合物;公司自成立以来,秉持“用质量作船, 以服务为帆,为科研服务”的企业理念,为国内外众多科研工作者提供了优质的服务及产品。