Host:Rabbit
Target Protein:PRAK
IR:Immunogen Range:89-190/473
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:8550
Swiss Prot:Q8IW41
Source:KLH conjugated synthetic peptide derived from human MAPKAPK5/PRAK:89-190/473
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The serine/threonine kinase PRAK is activated in response to cellular stress and proinflammatory cytokines, through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38 alpha, and MAPK11/p38 beta. PRAK has been reported to have a putative tumor suppressor function by mediating senescence upon activation by p38 in response to oncogenic ras. It is thought that phosphorylation of p53 by PRAK following activation of p38 MAPK by ras plays an important role in ras induced senescence and tumor suppression.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(2ug/Test)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Rabbit
本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: PRAK;MAPKAPK5;MAPKAPK5;p38调节/激活蛋白激酶抗体;PRAK MAPKAP kinase ;MAP kinase-activated;MAPKAP kinase 5;p38-regulated/activa;
上海沪震实业有限公司是一家集研发、生产和销售于一体的生命科学实验室产品生物科技企业。主营产品:试剂盒,ELISA试剂盒,抗体,重组蛋白,血清,胎牛血清,细胞,原代细胞 细胞培养试剂,常用生化试剂。