Host:Rabbit
Target Protein:phospho-MAPKAPK5 (Ser93)
IR:Immunogen Range:ES(p-S)PR
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:8550
Swiss Prot:Q8IW41
Source:KLH conjugated Synthesised phosphopeptide derived from human MAPKAPK5 around the phosphorylation site of Ser93:ES(p-S)PR
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The serine/threonine kinase PRAK is activated in response to cellular stress and proinflammatory cytokines, through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38 alpha, and MAPK11/p38 beta. PRAK has been reported to have a putative tumor suppressor function by mediating senescence upon activation by p38 in response to oncogenic ras. It is thought that phosphorylation of p53 by PRAK following activation of p38 MAPK by ras plays an important role in ras induced senescence and tumor suppression.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Cow
Horse
.
本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: MAPKAP kinase 5;phospho-MAPKAPK5;phospho S93;phospho Ser93;p38-regulated/activa;MAPKAPK5;MAPKAP kinase 5;p38-regulated/activa;
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