Rabbit Anti-BAMBI Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:BAMBI
IR:Immunogen Range:101-200/260
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:25805
Swiss Prot:Q13145
Source:KLH conjugated synthetic peptide derived from human BAMBI:101-200/260
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:BAMBI is a membrane spanning glycoprotein that acts as a negative regulator of TGF-β signaling during development. The BAMBI family of proteins are related to type I TGF-β receptor family, however, BAMBI is a pseudoreceptor that lacks an intracellular serine/threonine kinase domain. BAMBI transcription regulation is under the influence of β-catenin, BMP, smad3 and smad4. BAMBI expression can increase in colorectal and hepatocellular carcinomas relative to non-cancerous tissues. BAMBI is expressed at high levels during odontogenesis. BAMBI is coexpressed with Bmp-4 during early Xenopus embryogenesis and can be detected in poorly metastatic human melanoma cell lines
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Rabbit
Sheep
Guinea Pig
本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： BAMBI;BAMBI;BAMBI_HUMAN;BMP and activin;NMA;Non metastatic gene ;Non-metastatic gene ;Putative transmembra;
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