Rabbit Anti-IDH2 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:IDH2
IR:Immunogen Range:251-350/452
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:3418
Swiss Prot:P48735
Source:KLH conjugated synthetic peptide derived from human IDH2:251-350/452
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:IDH2 (isocitrate dehydrogenase 2 (NADP+), mitochondrial), also designated NADP+-specific ICDH; isocitrate dehydrogenase, mitochondrial; and oxalosuccinate decarboxylase, is a 452 amino acid enzyme encoded by the human gene IDH2. IDH2 belongs to the isocitrate and isopropylmalate dehydrogenases family and contains two nucleotide binding regions. IDH2 is involved in the reduction of NADP+ to NADPH and maintains the supply of glutathione (GSH) in mitochondria. It is believed to play a role in intermediary metabolism and energy production. IDH2 also tightly associates with the pyruvate dehydrogenase complex. IDH2 is found in the mitochondrion as a homodimer and can bind one magnesium or manganese ion per subunit.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(0.2ug/test)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Horse
本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： IDH2;mitochondrial;ICD-M;IDH;IDH2;IDHP_HUMAN;IDP;mNADP-IDH;
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