Rabbit Anti-PIM1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:PIM1
IR:Immunogen Range:251-350/404
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:5292
Swiss Prot:P11309
Source:KLH conjugated synthetic peptide derived from human PIM1:251-350/404
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(1ug/test)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Rabbit
Sheep
Guinea Pig
本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: PIM1;Oncogene PIM 1;Oncogene PIM1;pim 1 kinase 44 kDa ;PIM; pim1 kinase 44 kDa ;Pim2;PIM1_HUMAN;
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