Rabbit Anti-Haspin Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Haspin
IR:Immunogen Range:421-520/754
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:14841
Swiss Prot:Q9Z0R0
Source:KLH conjugated synthetic peptide derived from mouse Haspin:421-520/754
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Haspins is a protein family containing a distinctive C-terminal kinase domain and a divergent N-terminus. Haspin homologues occur within a diverse group of eukaryotes, including animals, plants and fungi, which suggests an early evolutionary origin. Haspin, a nuclear protein strongly expressed in male germ cells, is responsible for the phosphorylation of histone H3 at Thr-3. Depletion of Haspin RNA prevents normal alignment of chromosomes at metaphase, suggesting a crucial role for haspin during chromosome segregation. Expression of haspin also occurs in adult thymus and bone marrow, with weaker expression in adult prostate, intestine, lung, spleen, and lymph node. The gene encoding human haspin maps to chromosome 17p13.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
Cross Reactive Species:Human
Mouse
Rat
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： Haspin;germ cell associated;GSG2;H-Haspin;Haploid germ cell-sp;Serine/threonine;丝氨酸/苏氨酸蛋白激酶蛋白抗体;HASP_HUMAN;
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