Rabbit Anti-IL7R Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:IL7R
IR:Immunogen Range:251-350/459
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:3575
Swiss Prot:P16871
Source:KLH conjugated synthetic peptide derived from human IL-7Ra:251-350/459
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID).
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(1μg /test)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Horse
Rabbit
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： IL7R;IL-7Rα; IL-7Ra;CD 127;CD127;CD127 antigen;IL 7R; IL7RA_HUMAN;
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