Rabbit Anti-GDNFRA Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:GDNFRA
IR:Immunogen Range:351-429/465
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:2674
Swiss Prot:P56159
Source:KLH conjugated synthetic peptide derived from human GFR Alpha-1:351-429/465
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: GDNFRA;GDNF Receptor alpha ;GFRa-1;GFR alpha;TmR1;GFR alpha-1;RETL1;GFRA1_HUMAN;
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