Rabbit Anti-ATP1A1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:ATP1A1
IR:Immunogen Range:901-1023/1023
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:476
Swiss Prot:P05023
Source:KLH conjugated synthetic peptide derived from human ATP1A1:901-1023/1023
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The ubiquitously expressed sodium/potassium-ATPase (Na+/K+-ATPase) exists as a oligomeric plasma membrane complex that couples the hydrolysis of one molecule of ATP to the importation of three Na+ ions and two K+ ions against their respective electrochemical gradients. As a member of the P-type family of ion motives, Na+/K+-ATPase plays a critical role in maintaining cellular volume, resting membrane potential and Na+-coupled solute transport.The Alpha subunit contains the binding sites for ATP and the cations; the glycosylated Beta subunit ensures correct folding and membrane insertion of the Alpha subunits. The small subunit co-localizes with the Alpha subunit in nephron segments, where it increases the affinity of Na+/K+-ATPase for ATP. The Betasubunit, but not the subunit, is essential for normal activity of Na+/K+-ATPase.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-F(1:100-500)
ICC(1:100)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Rabbit
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： ATP1A1;A1A1;AT1A1;Atpa-1;MGC38419;MGC3285;Na(+)/K(+) ATPase 1;AT1A1_HUMAN;
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