中文名:(-)-表没食子儿茶素没食子酸酯
英文名:(-)-Epigallocatechin gallate
中文别名:3-没食子酸酯
英文别名:EGCG|EPIGALLOCATECHIN GALLATE [INCI]|Epigallocic acid|NCGC00164319-04|EGCG|NCGC00164319-01|UNII-BQM438CTEL|(-)-Epigallocatechin gallate (85% (-)-epigallocatechin gallate, 10% (-)-epigallocatechin, 5% (-)- epicatechin gallate)|SPECTRUM210239|Tox21_303457|S
纯度:98%
货号:E107404
包装:100mg、500mg
Cas号:989-51-5
存储温度:2-8°C储存
产品介绍:
(-)-Epigallocatechin Gallate (EGCG) is a strong polyphenol catechin antioxidant found in green tea, reported to have broad efficacy against many conditions generated from oxidative damage. Extensive oxidation of low density lipoproteins (LDLs) is correlated to cardiovascular diseases, and EGCG is reported to strongly inhibit Cu(2+)-mediated oxidative modification of LDLs. The antiapoptotic proteins Bcl-2 and Bcl-x(L) are observed to suppress apoptosis and convey survival to heavily damaged and mutated cells in vitro, and EGCG (along with the other catechins) is shown to directly inhibit these proteins, reestablishing the normal apoptotic pathway in the cell. EGCG also inhibits NOS2 (iNOS).An inhibitor of Bcl-2 and NOS2
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