中文名:阿德福韦酯
英文名:Adefovir Dipivoxil
中文别名:阿德伏韦酯 | 阿德幅韦二脂 | 9-[2-[双(新戊酰氧基甲氧基)磷酰甲氧基]乙基]腺嘌呤
英文别名:9-[2-[Bis(pivaloyloxymethoxy)phosphorylmethoxy]ethyl]adenine | 9-(2[bis(Pivaloyloxymethoxy)phosphorylmethoxy]ethyl)adenine
纯度:≥99%
货号:A129786
包装:100mg、25mg、250mg
Cas号:142340-99-6
存储温度:-20°C储存
产品介绍:
Adefovir Dipivoxil works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body. Target: NRTIs; HBV Adefovir Dipivoxil works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body. Adefovir Dipivoxil is used for treatment of hepatitis B and herpes simplex virus infection [1-3]. Adefovir Dipivoxil is approved for the treatment of chronic hepatitis B in adults with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (primarily ALT) or histologically active disease. Adefovir Dipivoxil is a failed treatment for HIV[3, 4].
Adefovir dipivoxil 是一种腺苷类似物,是核苷逆转录酶 (nucleoside reverse transcriptase) 抑制剂 Adefovir 的口服前体。Adefovir dipivoxil 对 Lamivudine 耐药株和野生型菌株均有抑制作用。Adefovir dipivoxil 具有抗正痘病毒活性。
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