uPAR产品信息
英文名称:Urokinase plasminogen activator surface receptor
中文名称:尿激酶型纤溶酶原激活物表面受体
靶点别称:uPAR,PLAUR,CD87,MO3
物种:Human / Mouse
标签:His Tag & Avi Tag / His Tag / Fc Tag
属性:Protein / Cell / Beads
标记:Biotin-labeled / FITC Labeled / Unconjugated / PE Labeled / APC Labeled
内毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
纯度(Purity)
>95% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
制剂(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重构方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
1. -20°C to -70°C for 12 months in lyophilized state;
2. -70°C for 3 months under sterile conditions after reconstitution.
uPAR分子背景
尿激酶纤溶酶原激活物表面受体(U-PAR)也称为PLAUR、单核细胞激活抗原Mo3、CD抗原CD87。PLAUR包含三个UPAR/Ly6结构域。U-PAR在大脑外侧区的神经元中表达(在蛋白质水平上),也在大脑中表达。PLAUR/CD87与MRC2、SRPX2和SORL1相互作用。PLAUR/UPAR作为尿激酶型纤溶酶原激活物的受体,在定位和促进纤溶酶形成方面发挥作用。U-PAR介导U-PA的蛋白水解非依赖性信号转导激活效应。
uPAR用户评价
关键字: uPAR;uPAR蛋白;PLAUR;CD87;CD87蛋白;
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