TGF-beta 3产品信息
英文名称:Transforming growth factor beta 3
中文名称:转化生长因子β3
靶点别称:TGFB3,ARVD,TGF-beta3
物种:Human
属性:Protein
标记:Unconjugated
内毒素(Endotoxin)
Less than 0.1 EU per μg by the LAL method.
无菌(Sterility)
The sterility testing was performed by membrane filtration method.
支原体(Mycoplasma)
Negative.
纯度(Purity)
>95% as determined by SDS-PAGE.
制剂(Formulation)
Lyophilized from 0.22 μm filtered solution in 50 mM HAC, pH2.8 with trehalose as protectant.
Contact us for customized product form or formulation.
重构方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
TGF-beta 3分子背景
转化生长因子β3(TGFB3)也称为TGF-β3,是转化生长因子-β超家族细胞因子的多肽成员。它是一种分泌的蛋白质,执行许多细胞功能,包括调节胚胎发生和细胞分化,是次级腭发育等各种过程所必需的。TGF-β3与TGF-β1和-β2相似,充当细胞开关,调节免疫功能、细胞增殖和上皮间质转化。整合素从LAP释放TGF-β-3:整合素结合导致LAP链扭曲,随后释放活性TGF-β-3。一旦LAP释放后被激活,TGF-β-3通过与TGF-β受体(TGFBR1和TGFBR2)结合起作用,TGF-β受体负责转导信号。
关键字: TGF-beta 3;TGFB3;转化生长因子β3;TGF-β3;TGFB3蛋白;
百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。