Human HE4 / WFDC2 Protein, His Tag
分子别名(Synonym)
HE4,WAP5,WFDC2,EDDM4
表达区间及表达系统(Source)
Human HE4, His Tag (HE4-H5223) is expressed from human 293 cells (HEK293). It contains AA Glu 31 - Phe 124 (Accession # AAH46106).
Predicted N-terminus: Glu 31
蛋白结构(Molecular Characterization)
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This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 10.9 kDa. The protein migrates as 19-23 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
内毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
纯度(Purity)
>95% as determined by SDS-PAGE.
制剂(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
Contact us for customized product form or formulation.
重构方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
![2.jpg 2.jpg](/SupplyImg1/2024-08-06/6385853833123998183859602.jpg)
![3.jpg 3.jpg](/SupplyImg1/2024-08-06/6385853833388391963413262.jpg)
背景(Background)
人附睾蛋白4(HE4)也称为WAP四二硫键核心结构域蛋白2(WFDC2)、附睾分泌蛋白E4、主要附睾特异性蛋白E4、推测蛋白酶抑制剂WAP5,是WFDC结构域家族的成员。HE4/WFDC2在肺上皮细胞中表达,也在一些卵巢癌中表达。WFDC结构域或WAP签名基序包含八个半胱氨酸,在蛋白质的核心形成四个二硫键,在许多家族成员中起蛋白酶抑制剂的作用。HE4也是一种小的分泌蛋白,可能参与精子成熟。
关键字: HE4;HE4蛋白;HE4重组蛋白;ACRO;百普赛斯;
百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。