2,2,6,6-四甲基哌啶（TEMP）

规格指标及物理特性

应用

1.用于制药中间体。

2.它已被用于吡啶-3-甲酰胺的高效邻位脱质子化。

3.有效的吡啶-3-羧胺去原质子化试剂。

2,2,6,6-Tetramethylpiperidine or TMP or HTMP is an organic compound of the amine class. In appearance, it is a colorless liquid and has a "fishy", amine-like odor. This amine is used in chemistry as a hindered base (hindered amine) because it can dissolve in organic solvents unlike inorganic bases such as potassium hydroxide. There are many ways to synthesis TMP. One method starts with a conjugate addition reaction of ammonia to phorone. The intermediate triacetone amine is then reduced in a Wolff-Kishner reaction.