P6803-100μg
Recombinant Murine Eotaxin/CCL11
100μg
2750.00元
Species
Gene ID
Accession
Source
Length
MW
Tag
Mouse
20292
P48298
E. coli
74aa
8.4kDa
－
Name
Recombinant Murine Eotaxin/CCL11 (Recombinant Murine Eotaxin/CCL11; rMuEotaxin/CCL11)；Recombinant Mouse Eotaxin/CCL11 ; 重组小鼠嗜酸性粒细胞趋化因子/CCL11
Synonyms
Eotaxin; C-C motif chemokine 11; chemokine (C-C motif) ligand 11; Eosinophil chemotactic protein; eotaxin; eotaxin-1; MGC22554; SCYA11Small-inducible cytokine A11; small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin)
Purity
>96% by SDS-PAGE and HPLC analyses.
Biological Activity
Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using purified eosinophils is in a concentration range of 100-1000ng/ml.
Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4.
Endotoxin
Less than 1EU/μg of rMuEotaxin/CCL11 as determined by LAL method.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.
Background
Murine CCL11 is belonging to the CC chemokine family. CCL11 was first purified from bronchoalveolar lavage fluid of guinea pigs. It was a strong and specific eosinophil chemoattractant in vitro. It can directly chemotactic for eosinophils, but not for monocytes or neutrophils. Murine CCL11 is approximately 63% identical at the amino acid level to human CCL11. In addition, CCL11 also shows about 60% amino acid sequence identity to human MCPs. CCR3 has been identified to be a specific CCL11 receptor.
Amino Acid Sequence
HPGSIPTSCC FIMTSKKIPN TLLKSYKRIT NNRCTLKAIV FKTRLGKEIC ADPKKKWVQD ATKHLDQKLQ TPKP
包装清单:
P6803-5μg
Recombinant Murine Eotaxin/CCL11
5μg
P6803-20μg
Recombinant Murine Eotaxin/CCL11
20μg
P6803-100μg
Recombinant Murine Eotaxin/CCL11
100μg
P6803-1mg
Recombinant Murine Eotaxin/CCL11
1mg
保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品仅限于专业人员的科学研究用，不得用于临床诊断或治疗，不得用于食品或药品，不得存放于普通住宅内。
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