Side effects of Ipamorelin

Ipamorelin (INN) (developmental code name NNC 26-0161) is a peptide selective agonist of the ghrelin/growth hormone secretagogue receptor (GHS) and a growth hormone secretagogue.It is a pentapeptide with the amino acid sequence Aib-His-D-2-Nal-D-Phe-Lys-NH2 that was derived from GHRP-1.

Benefits of Ipamorelin

Ipamorelin significantly increases plasma growth hormone (GH) levels in both animals and humans.In addition, ipamorelin stimulates body weight gain in animals.Like pralmorelin and GHRP-6, ipamorelin does not affect prolactin, follicle-stimulating hormone (FSH), luteinizing hormone (LH), or thyroid-stimulating hormone (TSH) levels.However, unlike pralmorelin (GHRP-2) and GHRP-6, but similarly to growth hormone-releasing hormone (GHRH), ipamorelin does not stimulate the secretion of adrenocorticotropic hormone (ACTH) or cortisol, and is highly selective for inducing the secretion only of GH.

Uses

Ipamorelin has been used by athletes as a performance enhancing drug.

Side effects

Ipamorelin is generally well-tolerated, with few side effects in most people who take it.  Side effects can depend on the dosage.  For our purposes, however, we are talking about ipamorelin designed for subcutaneous injection, as that is the format available from Invigor Medical (and, in fact, is one of the more common formats for anti-aging peptides today).  Side effects from Ipamorelin include:

Redness, itchiness, or irritation at the injection site, which usually is temporary;

Increased appetite/hunger (though this can also be due to the net effect of a boosted metabolism and more muscle mass gains);

Dry mouth;

Nausea;

Increased weight.