What are the adverse effects of Cyclohexylamine on humans?
Dec 1,2023
Cycloheximide is pharmacologically active and acts similarly to reserpine. A single dose administered orally or intravenously causes an increase in blood pressure; in this case, the mechanism of action is the release of norepinephrine from tissues of the nervous system. Studies have shown that peak cycloheximide blood levels of 0.5- 0.7 mg/L after a single oral dose in humans are sufficient to cause a significant increase in blood pressure.
In addition, prolonged exposure to cycloheximide-exposed areas may result in: (1) Methemoglobinemia - increased methemoglobin in the blood; this compound is classified as a secondary toxic effect. (2) Dermatotoxin - Skin burns. (3) Skin sensitiser - a substance that induces an allergic skin reaction. (4) Toxic Pneumonia - Inflammation of the lungs caused by inhalation of metal fumes or toxic gases and vapours.
References:
[1] COLLINGS A J. Metabolism of cyclamate and its conversion to cyclohexylamine.[J]. Diabetes Care, 1989, 12 1: 50-55; discussion 81-2. DOI:10.2337/diacare.12.1.50.
- Related articles
- Related Qustion
- Application of Cyclohexylamine Jun 27, 2022
Cyclohexylamine appears as a clear colorless to yellow liquid with an odor of ammonia. Flash point 90°F. Irritates the eyes and respiratory system.
The XeF4 Lewis structure consists of a central atom, xenon (Xe), and four outer atoms, fluorine (F), bonded at 90° and 180°. The xenon atom (Xe) and each fluorine atom (F) are connected by a single bond.....
Dec 1,2023APIEstradiol valerate/dienogest is a 4-phasic oral contraceptive approved for the prevention of pregnancy. The 4-phasic design allows for acceptable cycle control with this hormonal combination.....
Dec 1,2023DrugsCyclohexylamine
108-91-8You may like
- Cyclohexylamine
-
- $30.00 / 1kg
- 2024-08-15
- CAS:108-91-8
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 20 tons
- Cyclohexylamine
-
- $10.50 / 1KG
- 2024-08-09
- CAS:108-91-8
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10 ton
- Cyclohexylamine
-
- $90.00 / 10kilograms
- 2024-08-06
- CAS:108-91-8
- Min. Order: 10kilograms
- Purity: 99%
- Supply Ability: 100tons