What are the benefits of MK-0677 to the human body?

Introduction of MK-677

MK-677 (also known as ibutamoren), promotes the secretion of the growth hormone (GH) and increases insulin-like growth factor 1 (IGF-1). Ibutamoren increases growth hormone levels by mimicking the action of the hormone ghrelin and binding to one of the ghrelin receptors (GHSR) in the brain. Human studies have shown that it increases muscle mass and bone mineral density, making it a promising treatment for frailty in the elderly. It also alters the metabolism of body fat, so it may be used to treat obesity.

Benefits of MK-677

The benefits of MK-677 include muscle-building, a reduction in muscle wasting, better bone density, improved sleep, and anti-aging properties. It may also have nootropic effects and it can be beneficial in treating growth hormone deficiencies.

Helps Build Muscles

MK-677 is often used as an anabolic substance to increase lean body mass. It is orally active and can be taken once a day.MK-677 stimulates growth hormone and IGF-1, both of which are important for maintaining lean body mass. Many believe that growth hormone stimulates increases in muscle size and strength.

A study looking at 60 year olds showed that injections of stimulating growth hormone resulted in increased thigh muscle strength. However, in MK-677 Stimulated Muscle Growth, the results vary from person to person. In another study of 24 obese men, two months of treatment with ibuprofen increased lean body mass and briefly increased basal metabolic rate (BMR).

Reduces Muscle Wasting

MK-677 has shown in recent studies to alleviate muscle wasting that can be caused by a decline in protein within an individual’s diet. In one study a group of healthy young adults were tested to determine if MK-677 could reverse protein catabolism and the results proved to be quite positive. As a result, MK-677 is theorized to be possibly being an effective treatment for individuals who suffer from catabolic conditions.

Increases Bone Density

Several studies have indicated that long-term use of MK-677 can have tremendous results to increase bone mineral density. This finding can benefit several populations including obese individuals, older adults, and women with menopause. These distinct populations can have detrimental health problems due to low bone mineral density and MK-677 has proven to be an effective treatment for many of them. The groups of people who serve to benefit by MK-677’s ability to increase bone density must research the possibility of any long-term side effects since increases in bone density typically take more than a year’s use.

Improves Sleep

Since Growth Hormone is known to help improve sleep quality, it is commonly thought that Ibutamoren Mesylate can assist with sleep quality since it stimulates production in Growth Hormone. A study showed that in both younger and elderly subjects, ibutamoren improved sleep quality and REM (rapid eye movement) sleep duration.

Combats Aging and May Increase Longevity

Since MK-677 shares a lot of similar qualities to Ghrelin and binds to its receptors, it is believed that MK 677 can have the same effects on the brain that Ghrelin has. However, there are no studies that confirm whether or not MK 677 has direct nootropic effects on the brain. Scientists do have hope though that a couple of noticeable indirect methods may explain how MK 677 can be of assistance to cognitive function.

MK-677 can improve cognitive function by assisting individuals with the ability to get a good night’s rest. The ability of MK-677 to stimulate IGF-1 production can also indirectly improve cognitive function based on IGF-1’s role in cognitive function. One study indicated that IGF-1 positively affected participants’ ability to perform well on cognitive tests.

Beneficial in Treating Growth Hormone Deficiency

Ibutamoren can increase growth hormone, IGF-1, and IGFBP-3 levels in children with growth hormone deficiency. Furthermore, these effects are achieved without changing the concentrations of prolactin, glucose, triiodothyronine (T3), thyroxine (T4), thyrotropin, cortisol or insulin. In severely GH-deficient men, ibutamoren increased IGF-1 and growth hormone, with no significant changes in cortisol, PRL, and thyroid hormone levels. However, insulin and glucose were increased.