LUFFARIELLOLIDE

111149-87-2

CAS №: 111149-87-2

английское имя:: LUFFARIELLOLIDE

Синонимы:: LUFFARIELLOLIDE;3-[(3E,7E)-4,8-dimethyl-10-(2,6,6-trimethylcyclohexen-1-yl)deca-3,7-dienyl]-2-hydroxy-2H-furan-5-one;4-[(3E,7E)-4,8-Dimethyl-10-(2,6,6-trimethyl-1-cyclohexenyl)-3,7-decadienyl]-5-hydroxyfuran-2(5H)-one;4-[(3E,7E)-4,8-Dimethyl-10-(2,6,6-trimethyl-1-cyclohexen-1-yl)-3,7-decadienyl]-5-hydroxy-2(5H)-furanone;2(5H)-Furanone, 4-[(3E,7E)-4,8-dimethyl-10-(2,6,6-trimethyl-1-cyclohexen-1-yl)-3,7-decadien-1-yl]-5-hydroxy-

CBNumber:: CB0200705

Формула:: C25H38O3

молекулярный вес:: 386.57

MOL File:: 111149-87-2.mol

атрибут

безопасность

использование

поставщик 39

продукт поиска:

LUFFARIELLOLIDE атрибут

Температура кипения:	541.7±50.0 °C(Predicted)
плотность:	1.006±0.06 g/cm3(Predicted)
растворимость:	DMSO: soluble; Ethanol: soluble
пка:	9.98±0.40(Predicted)
форма:	Бледно-желтое масло.
InChI:	InChI=1S/C25H38O3/c1-18(11-7-13-21-17-23(26)28-24(21)27)9-6-10-19(2)14-15-22-20(3)12-8-16-25(22,4)5/h10-11,17,24,27H,6-9,12-16H2,1-5H3/b18-11+,19-10+
ИнЧИКей:	JPWPYTMXSXYUPG-QZPYEDBESA-N
SMILES:	O1C(O)C(CC/C=C(\C)/CC/C=C(\C)/CCC2C(C)(C)CCCC=2C)=CC1=O

Заявления о рисках и безопасности

LUFFARIELLOLIDE химические свойства, назначение, производство

Использование

Luffariellolide is a natural sesterterpenoid which reversibly inhibits secretory phospholipase A2 isoforms from bee venom (IC50 = 230 nM) and snake venom, reducing inflammation. It blocks the production of platelet-activating factor in stimulated neutrophils (IC50 = 5 μM). Luffariellolide is also a structural mimic of all-trans retinoic acid (RA) and, at 1 μM, acts as an agonist for the RA receptors RAR α, β, and γ but not for other nuclear receptors. In RA-sensitive cancer cell lines, luffariellolide induces the expression of RAR target genes and inhibits cell growth. It also inhibits the activation of hypoxia-inducible factor by hypoxia (IC50 = 3.6 μM).[Cayman Chemical]

LUFFARIELLOLIDE препаратная продукция и сырье

сырьё

препарат

LUFFARIELLOLIDE поставщик

Global( 39)Suppliers

поставщик	телефон	страна	номенклатура продукции	благоприятные условия
Aladdin Scientific	+1-+1(833)-552-7181	United States	52927	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	China	8474	58
TargetMol Chemicals Inc.	4008200310	China	24647	58
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	China	9806	58
Shanghai Easy CDMO Co.,Ltd	021-61734564	China	10010	58
Wuhan Topule	+86-02787215551 +86-19945035818	China	8206	58
Olix (Shanghai) Pharmaceutical Technology Co., Ltd	17316404525	China	9810	58
QUALITY CONTROL SOLUTIONS LTD.	0755-66853366; 13670046396	China	18899	58
Wuhan Augda Biotechnology Co., Ltd	15071299552	China	6712	58
Changzhou Bojia Biomedical Technology Co., Ltd.	2122619822	China	18488	58

111149-87-2()подобный поиск:

U-73343 Цитидин-5'-дифосфохолин натриевая соль гидрата Geranic кислота