6-broMo-8-cyclopentyl-5-Methyl-2-(5-(piperazin-1-yl)pyridin-2-ylaMino)pyrido[2,3-d]pyriMidin-7(8H)-one

851067-56-6

CAS №: 851067-56-6

английское имя:: 6-broMo-8-cyclopentyl-5-Methyl-2-(5-(piperazin-1-yl)pyridin-2-ylaMino)pyrido[2,3-d]pyriMidin-7(8H)-one

Синонимы:: Palbociclib C;Palbociclib-013;Pipemidic acid impurity BPO;Palbociclib Deboc Bromo Impurity / 6-Desacetyl-6-Bromo Palbociclib;6-Bromo-8-cyclopentyl-5-methyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one;6-broMo-8-cyclopentyl-5-Methyl-2-(5-(piperazin-1-yl)pyridin-2-ylaMino)pyrido[2,3-d]pyriMidin-7(8H)-one;6-Bromo-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-pyrido[2,3-d]pyrimidin-7(8H)-one;Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-bromo-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-;4-(6-((6-bromo-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate;Palbociclib impurity 16/6-broMo-8-cyclopentyl-5-Methyl-2-(5-(piperazin-1-yl)pyridin- 2-ylaMino)pyrido[2,3-d]pyriMidin-7(8H)-one

CBNumber:: CB02627155

Формула:: C22H26BrN7O

молекулярный вес:: 484.39

MOL File:: 851067-56-6.mol

атрибут

безопасность

использование

поставщик 48

продукт поиска:

6-broMo-8-cyclopentyl-5-Methyl-2-(5-(piperazin-1-yl)pyridin-2-ylaMino)pyrido[2,3-d]pyriMidin-7(8H)-one атрибут

Температура кипения:	682.2±65.0 °C(Predicted)
плотность:	1.495±0.06 g/cm3(Predicted)
растворимость:	Aqueous Acid (Slightly), DMSO (Slightly, Heated), DMF (Slightly, Heated)
пка:	8.66±0.10(Predicted)
форма:	Solid
цвет:	Off-White to Yellow
FDA UNII:	MGB9JX8TMP

Заявления о рисках и безопасности

6-broMo-8-cyclopentyl-5-Methyl-2-(5-(piperazin-1-yl)pyridin-2-ylaMino)pyrido[2,3-d]pyriMidin-7(8H)-one химические свойства, назначение, производство

Использование

6-Desacetyl-6-Bromo Palbociclib is an impurity of Palbociclib (P139900),(also known as compound number PD-0332991) is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.Also, it is derived from 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one (B682195), which is used to prepare pyridino[2,3-d]pyrimidin-7(8H)-one derivatives as CDK4 and/or CDK6 inhibitors useful in the treatment of diseases.

6-broMo-8-cyclopentyl-5-Methyl-2-(5-(piperazin-1-yl)pyridin-2-ylaMino)pyrido[2,3-d]pyriMidin-7(8H)-one препаратная продукция и сырье

сырьё

препарат

6-broMo-8-cyclopentyl-5-Methyl-2-(5-(piperazin-1-yl)pyridin-2-ylaMino)pyrido[2,3-d]pyriMidin-7(8H)-one поставщик

Global( 48)Suppliers

поставщик	телефон	страна	номенклатура продукции	благоприятные условия
Amadis Chemical Company Limited	571-89925085	China	131980	58
Arizest(Shanghai)Pharmatech Co., Ltd	+86-021-60753300	China	220	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	China	11927	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	China	23556	58
BOC Sciences	+1-631-485-4226	United States	19553	58
Arizest(Shanghai)Pharmatech Co.,Ltd	60753300-53010 13671599112	China	97	58
Shandong Chengchuang Blue Sea Pharmaceutical Technology Co., Ltd.	0531-58897130 15508676053	China	1932	58
Nanjing XiZe Biotechnology CO., Ltd.	025-66023220 0086-15250997978	China	7787	55
Shanghai Haohong Pharmaceutical Co., Ltd.	400-8210725 18016230971	China	24975	58
Nanjing Huanuo Biomedical Technology Co., Ltd	18913906212	China	6789	58

851067-56-6()подобный поиск:

Эверолимус Парекоксиб Палбоциклиб Эксеместан (Ацетилметилен) трифенилфосфоран