Дульцин
Дульцин атрибут
| Температура плавления: |
160-161℃ |
| Температура кипения: |
313.03°C (rough estimate) |
| плотность: |
1.199 |
| показатель преломления: |
1.5373 (estimate) |
| температура хранения: |
Sealed in dry,2-8°C |
| растворимость: |
ДМСО (Мало растворим), метанол (Мало растворим) |
| форма: |
Твердый |
| цвет: |
От белого до не совсем белого |
| Растворимость в воде: |
1,21 г/л (21°С) |
| λмакс: |
289nm(EtOH)(lit.) |
| Мерк: |
14,3464 |
| LogP: |
1.005 (est) |
| FDA 21 CFR: |
189.145 |
| Вещества, добавляемые в пищу (ранее EAFUS): |
DULCIN--PROHIBITED |
| Справочник по базе данных CAS: |
150-69-6 |
| Рейтинг продуктов питания EWG: |
1 |
| FDA UNII: |
8U78KF577Z |
| МАИР: |
3 (Vol. 12, Sup 7) 1987 |
| Система регистрации веществ EPA: |
Dulcin (150-69-6) |
Дульцин химические свойства, назначение, производство
Химические свойства
Off-White Solid
Использование
Dulcin is a non-nutritive sweetener. Dulcin is a sweet analgesic for use in medical procedures or treatments.
Методы производства
4-Ethoxyphenylurea, dulcin, is produced from the addition of potassium cyanate to p-phenetidine hydrochloride in aqueous solution at room temperature or from mixing urea and p-phenetidine hydrochloride to a mixture of hydrochloric acid and glacial acetic acid.
Общее описание
White crystals.
Реакции воздуха и воды
Partially decomposes on heating in water; hydrolyzes in 0.1 N acetic acid. Slightly water soluble .
Профиль реактивности
DULCIN is an example of an amide. Amides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Профиль безопасности
Human poison by
ingestion. Moderately toxic experimentally
by ingestion. Human systemic effects by
ingestion: somnolence, hallucinations,
distorted perceptions, and changes in motor
activity. In adults 20 to 40 g produces
dizziness, nausea, methemoglobinemia,
cyanosis, and hypotension. Questionable
carcinogen with experimental tumorigenic
data. When heated to decomposition it
emits toxic fumes of NOx.
Дульцин препаратная продукция и сырье
сырьё
препарат
Дульцин поставщик
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