5,7-dihydroxychromone
|
31721-94-5
|
- CAS №
- 31721-94-5
- английское имя:
- 5,7-dihydroxychromone
- Синонимы:
- 7-Dihydroxychromone;5,7-Dihydroxy-4-chromone;5,7-Dihydroxychromen-4-one;5,7-Dihydroxy-4H-chroMen-4-one;5,7-Dihydroxy-γ-chromene-4-one;5,7-Dihydroxy-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 5,7-dihydroxy-;Arenavirus,5,7 Dihydroxychromone,inhibit,Inhibitor,PARP,Caspase,Keap1-Nrf2,5,7-Dihydroxychromone,5,7Dihydroxychromone,poly ADP ribose polymerase
- CBNumber:
- CB11304153
- Формула:
- C9H6O4
- молекулярный вес:
- 178.14
- MOL File:
- 31721-94-5.mol
|
5,7-dihydroxychromone атрибут
| Температура плавления: |
232-273℃ |
| Температура кипения: |
399℃ |
| плотность: |
1.563 |
| Fp: |
171℃ |
| температура хранения: |
2-8°C |
| растворимость: |
нерастворим в H2O; ≥5,41 мг/мл в этаноле при осторожном нагревании; ≥7,05 мг/мл в ДМСО |
| форма: |
Твердый |
| пка: |
6.57±0.20(Predicted) |
| цвет: |
White to light yellow |
безопасность
- Заявления о рисках и безопасности
- код информации об опасности(GHS)
5,7-dihydroxychromone химические свойства, назначение, производство
Описание
5,7-Dihydroxychromone is a flavone decomposition product that has been found in A. hypogaea and has diverse biological activities, including antimicrobial, antioxidant, and neuroprotective properties. It reduces radial growth of the soil pathogenic fungi R. solani and S. rolfsii (IC50s = 18 and 26 μM, respectively) but has no effect on soil pathogenic bacteria of the genus Bradyrhizobium. 5,7-Dihydroxychromone (0.4, 2, and 10 μM) reduces increases in apoptosis and the levels of reactive oxygen species (ROS) induced by 6-OHDA in SH-SY5Y neuroblastoma cells. It also increases the levels of HO-1, NQO1, and GCLc in SH-SY5Y cells when used at concentrations ranging from 0.08 to 10 μM.
5,7-dihydroxychromone препаратная продукция и сырье
сырьё
препарат
5,7-dihydroxychromone поставщик
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