1,3-DICHLORO-5-[(1E)-2(4-TRIFLUOROMETHYLPHENYL)ETHENYL]-BENZENE

688348-33-6

CAS №: 688348-33-6

английское имя:: 1,3-DICHLORO-5-[(1E)-2(4-TRIFLUOROMETHYLPHENYL)ETHENYL]-BENZENE

Синонимы:: CAY10465;CAY10465 Exclusive;CAY10465;CAY-10465;CAY 10465;1,3-Dichloro-5-(4-(trifluoromethyl)styryl)benzene;1,3-DICHLORO-5-[(1E)-2(4-TRIFLUOROMETHYLPHENYL)ETHENYL]-BENZENE;1,3-dichloro-5-{(E)-2-[4-(trifluoromethyl)phenyl]ethenyl}benzene;CAY-10465,AhR,CAY 10465,inhibit,Inhibitor,Aryl Hydrocarbon Receptor;Benzene, 1,3-dichloro-5-[(1E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-

CBNumber:: CB1397651

Формула:: C15H9Cl2F3

молекулярный вес:: 317.13

MOL File:: Mol file

атрибут

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использование

поставщик 39

продукт поиска:

1,3-DICHLORO-5-[(1E)-2(4-TRIFLUOROMETHYLPHENYL)ETHENYL]-BENZENE атрибут

Температура кипения:	361.2±42.0 °C(Predicted)
плотность:	1.378±0.06 g/cm3(Predicted)
температура хранения:	Store at -20°C
растворимость:	DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2)(1:1): .5 mg/ml; Ethanol: 20 mg/ml
форма:	Кристаллическое твердое вещество
цвет:	White to off-white

Заявления о рисках и безопасности

1,3-DICHLORO-5-[(1E)-2(4-TRIFLUOROMETHYLPHENYL)ETHENYL]-BENZENE химические свойства, назначение, производство

Описание

The aryl hydrocarbon receptor (AhR) is a ligand-dependent intracellular transcription factor whose ligands include some of the most infamous xenobiotics, including dioxin, benzo[a]pyrene, and numerous polyaromatics from soot and coal tar. CAY10465 is an analog of resveratrol acting as a potent and selective AhR agonist, with a K_i of 0.2 nM. CAY10465 is inactive as a ligand for the estrogen receptor even at 100 μM.

Использование

(E)-1-[4-(Trifluoromethyl)phenyl]-2-(3,5-dichlorophenyl)ethene is a stilbene derivative of resveratrol and a selective aryl hydrocarbon receptor agonist.

1,3-DICHLORO-5-[(1E)-2(4-TRIFLUOROMETHYLPHENYL)ETHENYL]-BENZENE препаратная продукция и сырье

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1,3-DICHLORO-5-[(1E)-2(4-TRIFLUOROMETHYLPHENYL)ETHENYL]-BENZENE поставщик

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