23-HYDROXYBETULINIC ACID
23-HYDROXYBETULINIC ACID атрибут
| Температура плавления: |
>293°C (dec.) |
| Температура кипения: |
585.8±25.0 °C(Predicted) |
| плотность: |
1.106 |
| температура хранения: |
-20°C Freezer, Under inert atmosphere |
| растворимость: |
Метанол (Слабо растворимый, нагретый), пиридин (Слабо растворимый) |
| форма: |
Твердый |
| пка: |
4.60±0.70(Predicted) |
| цвет: |
белый |
Заявления о рисках и безопасности
23-HYDROXYBETULINIC ACID химические свойства, назначение, производство
Описание
23-hydroxy Betulinic acid is a triterpenoid that has been found in P. chinensis and has anticancer activity. It inhibits proliferation of K562, B16, and HeLa cells (IC50s = 39.9, 78.5, and 80 μM, respectively), as well as human umbilical vein endothelial cells (HUVECs; IC50 = 94.8 μM). It halts the cell cycle at the S phase and induces apoptosis in K562 cells in a concentration-dependent manner with a loss of the mitochondrial membrane potential and an increase in Bax and cytochrome C protein levels.
Использование
23-Hydroxybetulinic Acid is a potential cytoxic agent in the treatment of cancer. Apoptotic effect. Antiproliferative.
23-HYDROXYBETULINIC ACID препаратная продукция и сырье
сырьё
препарат
23-HYDROXYBETULINIC ACID поставщик
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