4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt
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206443-06-3
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- CAS №
- 206443-06-3
- английское имя:
- 4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt
- Синонимы:
- 4-Methyl-7-[(6-O-sulfo-β-D-galactopyranosyl)oxy]-;4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt;4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate Sodium Salt;4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate sodium salt;4-Methylumbelliferyl β-D-galactopyranoside-6-sulphate sodium salt;4-Methylumbelliferyl β-D-galactopyranoside-6-sulphate sodium salt;[(3R,4S,5S,6S)-3,4,5-trihydroxy-6-(4-methyl-2-oxochromen-7-yl)oxyoxan-2-yl]methyl sulfate;4-Methyl-7-[(6-O-sulfo-beta-D-galactopyranosyl)oxy]-2H-1-benzopyran-2-one monosodium salt;2H-1-Benzopyran-2-one, 4-methyl-7-[(6-O-sulfo-β-D-galactopyranosyl)oxy]-, monosodium salt (9CI);[(3R,4S,5S,6S)-3,4,5-trihydroxy-6-(4-methyl-2-oxo-chromen-7-yl)oxy-tetrahydropyran-2-yl]methoxysulfonyloxysodium
- CBNumber:
- CB21231629
- Формула:
- C16H17NaO11S
- молекулярный вес:
- 440.35435
- MOL File:
- 206443-06-3.mol
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4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt атрибут
| Температура плавления: |
196-198?C |
| температура хранения: |
-20°C Freezer, Under Inert Atmosphere |
| растворимость: |
Метанол (слегка обработан ультразвуком), вода (слегка) |
| форма: |
Твердый |
| цвет: |
От белого до не совсем белого |
| Стабильность:: |
-20°C Морозильник, в инертной атмосфере |
4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt химические свойства, назначение, производство
Описание
4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate (sodium salt) (4-MU-Gal-6S) is a fluorogenic substrate used to quantify N-acetylgalactosamine-6-sulphatase (GALNS) activity. 4-MU-Gal-6S is cleaved by GALNS to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases. It has been used to detect Morquio disease type A, a lysosomal storage disorder in which GALNS is deficient. 4-MU-Gal-6S can be used to assess GALNS activity in a very small blood volume to determine the extent of deficiency.
Химические свойства
White Solid
Использование
4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt is used for the determination of galactose-6-sulphate sulphatase activity,it is used in the diagnosis of Mucopolysaccharidosis IV A.
4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt препаратная продукция и сырье
сырьё
препарат
4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt поставщик
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