Далфопристин

112362-50-2

CAS №: 112362-50-2

Химическое название:: Далфопристин

английское имя:: Dalfopristin

Синонимы:: RP 54476;Dalfopristin;Dalfopristin Mesylate;RP-54476,RP 54476,Inhibitor,Dalfopristin,Antibiotic,Bacterial,inhibit;(3R,4R,5E,10E,12E,14S,26R,26aS)-26-[[2-(Diethylamino)ethyl]sulfonyl]-8,9,14,15,24,25,26,26a-octahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-3H-21,18-nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadi;(3R,4R,5E,10E,12E,14S,26R,26aS)-26-[[2-(DiethylaMino)ethyl]sulfonyl]-8,9,14,15,24,25,26,26a-octahydro-14-hydroxy-4,12-diMethyl-3-(1-Methylethyl)-3H-21,18-nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetr;(3R,4R,5E,10E,12E,14S,26R,26aS)-26-[[2-(Diethylamino)ethyl]sulfonyl]-8,9,14,15,24,25,26,26a-octahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-3H-21,18-nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone;3H-21,18-Nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone, 26-[[2-(diethylamino)ethyl]sulfonyl]-8,9,14,15,24,25,26,26a-octahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-, (3R,4R,5E,10E,12E,14S,26R,26aS)-

CBNumber:: CB31075198

Формула:: C34H50N4O9S

молекулярный вес:: 690.85

MOL File:: 112362-50-2.mol

атрибут

безопасность

использование

поставщик 69

продукт поиска:

Далфопристин атрибут

Температура плавления:	~150°
Температура кипения:	940.5±65.0 °C(Predicted)
плотность:	1.27±0.1 g/cm3(Predicted)
температура хранения:	Store at -20°C
растворимость:	DMSO:113.0(Max Conc. mg/mL);163.57(Max Conc. mM) Ethanol:100.0(Max Conc. mg/mL);144.75(Max Conc. mM)
форма:	Solid
пка:	13.18±0.70(Predicted)
цвет:	White to yellow
FDA UNII:	R9M4FJE48E

Заявления о рисках и безопасности

Банк данных об опасных веществах	112362-50-2(Hazardous Substances Data)

Далфопристин химические свойства, назначение, производство

Использование

Dalfopristin is a semi-synthetic analogue of ostreogyrcin A (virginiamycin M, pristinamycin IIA, streptogramin A) formed by addition of diethylaminoethylthiol to the 2-pyrroline group of ostreogyrcin, followed by oxidation to the sulphone. The structural changes provide a more hydrophobic compound with a readily ionisable group for generating a salt. Dalfopristin is used commercially in synergistic combination with quinupristin (70:30). There is little published data on the synthesis, biological or antibiotic activity of dalfopristin alone, however the combination product is highly effective, including activity against antibiotic resistant strains.

Далфопристин препаратная продукция и сырье

сырьё

препарат

Далфопристин поставщик

Global( 69)Suppliers

поставщик	телефон	страна	номенклатура продукции	благоприятные условия
Amadis Chemical Company Limited	571-89925085	China	131980	58
Aladdin Scientific	+1-+1(833)-552-7181	United States	57511	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	China	33350	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	China	8474	58
InvivoChem	+1-708-310-1919 +1-13798911105	United States	6393	58
BOC Sciences	16314854226; +16314854226	United States	19743	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	China	30250	58
Nanjing Shizhou Biology Technology Co.,Ltd	025-85560043 15850508050	China	12007	58
Hubei wei shi reagent group ltd., company	027-02759101766 13125137661	China	4499	58
Olix (Shanghai) Pharmaceutical Technology Co., Ltd	17316404525	China	9718	58

112362-50-2(Далфопристин)подобный поиск:

Индол-2-карбоновой кислоты Ацебутолол Сульбактам Тигециклин Морфолин Далфопристин