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Fiacitabine

 структура
69123-90-6
CAS №
69123-90-6
английское имя:
Fiacitabine
Синонимы:
FOAC;FIAC;NSC382097;NSC 382097;NSC -82097;Fiacitabine;NSC-382097;FIAC;FICA, NSC382097, FOAC;Fiacitabine (NSC-382097;FOAC|||FIAC|||NSC 382097
CBNumber:
CB31178749
Формула:
C9H11FIN3O4
молекулярный вес:
371.1
MOL File:
69123-90-6.mol

Fiacitabine атрибут

Температура кипения: 524.6±60.0 °C(Predicted)
плотность: 2.44±0.1 g/cm3(Predicted)
температура хранения: Store at -20°C
растворимость: DMSO: ≥ 37 mg/mL (99.70 mM)
пка: 12.84±0.70(Predicted)
форма: пудра
цвет: White to off-white
FDA UNII: 4058H365ZB

Заявления о рисках и безопасности

Fiacitabine химические свойства, назначение, производство

Описание

Fiacitabine is a pyrimidine nucleoside analog with activity against various herpesviruses. It is converted to its triphosphate form in vivo and inhibits viral DNA polymerase. It has been used in trials studying the treatment of HIV Infections and Cytomegalovirus Infections.

Способ действия

Fiacitabine is an antimicrobial agent that inhibits microbial growth by binding to the ribosomal 30S subunit and blocking protein synthesis. It is a prodrug that is converted to 5-fluorocytosine (5FC) in the liver, where it inhibits the activity of the enzyme dihydropyrimidine dehydrogenase, thereby interfering with DNA replication.

Fiacitabine препаратная продукция и сырье

сырьё

препарат


Fiacitabine поставщик

Global( 44)Suppliers
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SHANGHAI T&W PHARMACEUTICAL CO., LTD.
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China 5738 58
CONIER CHEM AND PHARMA LIMITED
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China 49374 58
BOC Sciences
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United States 19553 58

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